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YNiC seminar 29th July
by Rebecca E Millman 26 Jul '10

26 Jul '10

Dear Users This week (4-5 pm YNiC open plan) Matt Brookes from the University of Nottingham will give a talk on "Brain network measurements using MEG and ultra-high field MRI". http://www.nottingham.ac.uk/neuroscience/contact/a-z/A-F/brookes_matt.phtml Everyone is welcome to attend. Best wishes Rebecca -- ************************************************************************ Dr. Rebecca E. Millman Science Liaison Officer York Neuroimaging Centre The Biocentre York Science Park Heslington YO10 5DG Tel: +44 (0) 1904 567614 Fax: +44 (0) 1904 435356

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Seminar next week
by Gary Green 23 Jul '10

23 Jul '10

Apologies for cross-posting this to people in several email lists Next week we have two seminars on Thursday the 29th in the YNiC Open Plan area. At 2pm There will be a talk entitled "NMR and MRI sensitivity enhancement by Parahydrogen Induced Polarization" by Kerstin Münnemann Max Planck Institute for Polymer Research, Mainz, Germany Despite its wide applicability in chemistry, biology and medicine, Nuclear Magnetic Resonance (NMR) spectroscopy still suffers from its inherently low sensitivity. Exploiting the large signal enhancements associated with hyperpolarization techniques, such as Parahydrogen Induced Polarization (PHIP), however, NMR or MRI qualify for monitoring dynamic processes in real time. In this lecture, the synthesis and hyperpolarization of several biocompatible molecules like barbiturates, Vinylpyrrolinidon (blood plasma expander) or Dimethylcarboxylat (precursor to fumarate) will be presented. Polarization transfer to 13C in these molecules by using adequate pulse sequences is demonstrated. Moreover, constant NMR signal enhancement of 1H and 13C is shown using a continuous delivery of parahydrogen by hollow fiber membranes. This allows the acquisition of two-dimensional NMR experiments requiring multiple excitations with constant initial polarization. The membrane technique can be easily extended to produce a continuous flow of a hyperpolarized liquid as will be shown for MRI applications. All are welcome A separate email will announce the 4pm talk Gary -- Gary Green York Neuroimaging Centre The Biocentre York Science Park Innovation Way Heslington York YO10 5DG http://www.ynic.york.ac.uk https://www.ynic.york.ac.uk/about-us/people/ggrg tel. +44 (0) 1904 435349 PA (Richard Lee) +44 (0) 1904 435329 fax +44 (0) 1904 435356 mobile +44 (0) 788 191 3004

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Re: Job offer
by Gary Green 21 Jul '10

21 Jul '10

Wolfgang.Kilian(a)ptb.de wrote: > More information may be found on the web > > http://www.ptb.de/de/jobsausbildung/stellen/index.php?id=1163&no_cache=1&L=… > [tt_news]=2604&tx_ttnews[backPid]=96&cHash=d8268827b6 > http://ib.ptb.de/en/org/8/81/811/ResearchTopics/Hyperpolarization.html > > > > > Best regards > > Dr. Wolfgang Kilian > Physikalisch-Technische Bundesanstalt > Abbestr. 2-12 > 10587 Berlin > > Tel.: ++49-30-3481-7952 > Fax.: ++49-30-3481-7507 > E-Mail: wolfgang.kilian(a)ptb.de

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Visitors to YNiC
by Sam Johnson 19 Jul '10

19 Jul '10

Hello all, Just to let people know there there are a couple of visits to YNiC this week that might have an impact on you. Tomorrow (Tuesday) between 1:30 and about 2:30, and Wednesday morning, between 10 and 11 there will be groups in open plan. Both groups are pretty small and won't be using the computers so hopefully it won't be too disruptive. There will however be presentations, so you may rather have a late lunch tomorrow and a prolonged coffee on Wednesday. Thanks, and apologies for any inconvenience, Sam

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Important issue about scanning
by Gary Green 14 Jul '10

14 Jul '10

Dear Users At this time of year it can be hard to recruit participants. It is therefore very tempting to recruit close friends and relatives. One of the ethical issues that arises from taking this route for recruitment is that it might be difficult for a friend or relative to turn down your request. Unfortunately, if they accept then it then places you and us in a rather difficult position if an anomaly is spotted on the scan. This is extremely difficult to deal with if the investigator is in the control room when the anomaly is detected. We already have a policy that prevents staff from scanning relatives. We now will extend this to the scanning of all close relatives. I hope that you can understand the reasons behind this decision. The radiographers have been asked to, politely, refuse to scan relatives of investigators. Thanks Gary -- Gary Green York Neuroimaging Centre The Biocentre York Science Park Innovation Way Heslington York YO10 5DG http://www.ynic.york.ac.uk https://www.ynic.york.ac.uk/about-us/people/ggrg tel. +44 (0) 1904 435349 PA (Richard Lee) +44 (0) 1904 435329 fax +44 (0) 1904 435356 mobile +44 (0) 788 191 3004

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Busy times
by Antony Morland 09 Jul '10

09 Jul '10

Dear All, The booking system is now back to normal service. You will see however that all research time is booked until the end of July. If you have an urgent need for scan time before then, please get in touch and we will attempt to get scans performed for you. Best wishes Tony

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Re: Temporary Block on Booking
by Antony Morland 09 Jul '10

09 Jul '10

Hi All, To clarify: All currently booked slots will be honoured. It is just the ability to book NEW slots that is being temporarily suspended. Tony Andy Young wrote: > Hello Tony, > > I'm hoping you mean you've suspended ability to book new slots, but > existing bookings will be honoured. > > My students have participants coming in today. > > Cheers, > > Andy. > > > >> Dear All, >> >> I have temporarily suspended the ability to book scan slots until the >> end of July. I hope to allow normal booking procedures to be reset by >> the end of the day (Friday 9th July). Unfortunately, I have had to take >> this action because some projects that have strict deadlines for >> completion have struggled obtain sufficient scan hours under the current >> system of booking. I will be consulting with the project teams to >> resolve this today. Rest assured that all the research time between now >> and the end of July will not be booked as a result of this consultation >> process. >> >> I will update this list, when normal service resumes. >> >> Best wishes >> >> Tony >> >> -- >> ynic-users mailing list >> ynic-users(a)ynic.york.ac.uk >> https://www.ynic.york.ac.uk/mailman/listinfo/ynic-users >> >> > > >

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Temporary Block on Booking
by Antony Morland 09 Jul '10

09 Jul '10

Dear All, I have temporarily suspended the ability to book scan slots until the end of July. I hope to allow normal booking procedures to be reset by the end of the day (Friday 9th July). Unfortunately, I have had to take this action because some projects that have strict deadlines for completion have struggled obtain sufficient scan hours under the current system of booking. I will be consulting with the project teams to resolve this today. Rest assured that all the research time between now and the end of July will not be booked as a result of this consultation process. I will update this list, when normal service resumes. Best wishes Tony

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YNiC seminar today
by rem 08 Jul '10

08 Jul '10

Dear Users Today (4 pm in YNiC) there will be a talk by Lee Harrison from YNiC. The title of Lee's talk is "Bayesian Inference in Neuroimaging". Abstract: "Analyzing data involves quantifying the uncertainties inherent in their production, e.g. measurement noise. A way to achieve this is to formulate models in terms of probabilities, in other words, Bayesian models. A Bayesian approach provides a language to formally represent such uncertainty and the tools necessary to manipulate these notions in a coherent manner. The aim of this talk is to give an overview of some of the ideas and rhetoric used in constructing Bayesian models, estimating them and applying them to neuroimaging problems. The talk is based on an introduction to Bayesian inference given at the Statistical Parametric Mapping (SPM) short course. The emphasis will be on applications and not the equations. For example, using Dynamic Causal Models (DCM) to ask questions about interactions between cortical regions and spatial models to implement a computational model of how an observer represents uncertainty in a sequence of events." Everyone is welcome to attend. Best wishes Rebecca -- ************************************************************************ Dr. Rebecca E. Millman Science Liaison Officer York Neuroimaging Centre The Biocentre York Science Park Heslington YO10 5DG Tel: +44 (0) 1904 567614 Fax: +44 (0) 1904 435356

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YNiC seminar 8th July
by rem 05 Jul '10

05 Jul '10

Dear Users This week (4 pm in YNiC) there will be a talk by Lee Harrison from YNiC. The title of Lee's talk is "Bayesian Inference in Neuroimaging". Abstract: "Analyzing data involves quantifying the uncertainties inherent in their production, e.g. measurement noise. A way to achieve this is to formulate models in terms of probabilities, in other words, Bayesian models. A Bayesian approach provides a language to formally represent such uncertainty and the tools necessary to manipulate these notions in a coherent manner. The aim of this talk is to give an overview of some of the ideas and rhetoric used in constructing Bayesian models, estimating them and applying them to neuroimaging problems. The talk is based on an introduction to Bayesian inference given at the Statistical Parametric Mapping (SPM) short course. The emphasis will be on applications and not the equations. For example, using Dynamic Causal Models (DCM) to ask questions about interactions between cortical regions and spatial models to implement a computational model of how an observer represents uncertainty in a sequence of events." Everyone is welcome to attend. Best wishes Rebecca -- ************************************************************************ Dr. Rebecca E. Millman Science Liaison Officer York Neuroimaging Centre The Biocentre York Science Park Heslington YO10 5DG Tel: +44 (0) 1904 567614 Fax: +44 (0) 1904 435356

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