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Reminder: YNiC seminar today!
by Rebecca Lowndes 25 May '23

25 May '23

Today's seminar at 4pm in person or on zoom. Refreshments will be provided. https://york-ac-uk.zoom .us/j/96762553290?pwd=UEluT1lMd3V5azY5YzNmWkJCV1VTdz09 <https://www.google.com/url?q=https://york-ac-uk.zoom.us/j/96762553290?pwd%3…> The role of localised sleep spindles in adaptive memory consolidation Summary: Sleep spindles are 12-15Hz waxing and waning neural oscillations occurring during non-rapid eye movement sleep. They are believed to be mechanistically involved in memory consolidation, the strengthening and stabilisation of recently acquired memories, through inducing LTP and synaptic plasticity in learning-related hippocampal-cortical networks. A recent framework proposes that spindle-mediated memory consolidation should favour so-called adaptive memories, those experiences that are personally salient or goal-relevant. In this talk, I will present an outline for a study designed to directly test this hypothesis for the first time. I will employ a lateralised encoding task and present stimuli to a single visual field that should create distinct encoding representations in the contralateral hemisphere. Memory for items in one visual field will be prioritised for consolidation by being associated with a financial reward if remembered at a post-sleep test. I hypothesise that during sleep, sleep spindle activity will be heightened over the rewarded hemisphere (compared with unrewarded), and that this spindle activity will correlate with memory for the high-reward items. See you all there Becky -- Rebecca Lowndes Research Technician York Neuroimaging Centre

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This Week at YNiC
by Jennifer Ashton 23 May '23

23 May '23

Hello, Please find details about upcoming inductions and training below. Please also note that we have a seminar this Thursday (see details below), it would be great to see you there! *YNiC User Inductions* If you are aware of any new students/staff that will require access to YNiC and/or an IT account, they must attend a YNiC user induction. Our next induction will be on *Friday the 2nd of June, at 13:00*. Please ask them to contact support(a)ynic.york.ac.uk to sign up. *Level 0 operator training* *The next L0 training session will be held on Wednesday the 14th of June, 13:00-15:00. * Please note that users requesting Level 0 training should be a PhD, RA/Postdoc, or staff, and should already have a project proposal submitted to YNiC. Please email support(a)ynic.york.ac.uk if you have any questions or wish to book on to this session. Please note that sessions are limited to 4 trainees, which will be allocated on a first-come first-served basis. Training must be booked at least a week before the session date, in order to reserve the scanner booking. *Seminar* The next YNiC seminar will be this *Thursday (25th of May) at 4pm* with a talk from *Dr Dan Denis *titled "*The role of localised sleep spindles in adaptive memory consolidation"*. It would be great to see you here at YNiC, where refreshments will be available after the talk. You can also use the following link to catch the seminar on zoom https://york-ac-uk.zoom .us/j/96762553290?pwd=UEluT1lMd3V5azY5YzNmWkJCV1VTdz09 <https://www.google.com/url?q=https://york-ac-uk.zoom.us/j/96762553290?pwd%3…> Have a great week! Many thanks, Jennifer -- Jennifer Ashton, PhD Senior Research Technician York Neuroimaging Centre Working days: Monday, Tuesday and Wednesday

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YNiC Seminar - TOMORROW
by Rebecca Lowndes 10 May '23

10 May '23

Hi all, Don't forget we have a YNiC seminar by *Dr Tirso Gonzalez Alam *titled "*Visual to default network pathways: A double dissociation between semantic and spatial cognition**" *tomorrow (Thursday) at 4pm. The seminar will be in person at YNiC. You can also use the following link to catch the seminar on zoom https://york-ac-uk.zoom .us/j/96762553290?pwd=UEluT1lMd3V5azY5YzNmWkJCV1VTdz09 <https://www.google.com/url?q=https://york-ac-uk.zoom.us/j/96762553290?pwd%3…> See you there! Becky *Visual to default network pathways: A double dissociation between semantic and spatial cognition* Tirso Gonzalez-Alam, Katya-Krieger-Redwood, Dominika Varga, Zhiyao Gao, Aidan Horner, Tom Hartley, Magdalena Sliwinska, David Pitcher, Jonathan Smallwood, Elizabeth Jefferies *Abstract* The Default Mode Network (DMN) often deactivates to visual input yet it can couple to visual cortex, and it is composed of multiple subsystems that might differ in their degree of visual coupling or in the memory representations that they support. We used a combination of univariate, connectivity and multivariate fMRI analyses across three samples (combined N > 250) to investigate the architecture connecting visual cortex to DMN, and the engagement of visual-DMN pathways in memory-guided decisions across two domains (semantic and spatial). Participants learned virtual environments consisting of buildings populated with objects, with half of the buildings containing objects from a single semantic category allowing them to associate space with meaning. In a second session, they made spatial and semantic decisions about these buildings and objects in the scanner. We found semantic and spatial judgements engaged distinct DMN subsystems. Frontotemporal DMN regions were primarily engaged by semantic judgements and showed stronger connectivity to object perception regions in lateral ventral occipital cortex, while medial temporal DMN regions were more strongly recruited during spatial judgements and showed stronger connectivity to medial visual regions involved in processing scenes. Clusters in angular gyrus and ventral lateral occipital cortex, topographically situated between these pathways, were implicated in the integration of semantic and spatial information, suggesting a mechanism for the interaction of these distinct visual-to-DMN pathways. These results show how processing streams that capture different unimodal to heteromodal transformations relevant to conceptual and spatial processing might interact at multiple levels of the cortical hierarchy to produce coherent cognition. -- Rebecca Lowndes Research Technician York Neuroimaging Centre

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Siemens MRI down for repair
by Andre Gouws 09 May '23

09 May '23

Hi all, We encountered and error with the Siemens MRI scanner today. The engineers are being booked in to resolver the issue and we hope it will be a relatively quick fix. We will keep you posted, but as it stand the system is down as it requires some parts. More news will follow as soon as we have any, -- André ************************************************************************ André Gouws PhD Lead Technical Specialist York Neuroimaging Centre and York Diagnostic Imaging Departmental Safety Advisor - Dept. of Psychology University of York The Biocentre York Science Park Heslington YO10 5NY

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This Week at YNiC
by Jennifer Ashton 03 May '23

03 May '23

Hello, Please find details about upcoming inductions and training below. Please also note that the seminar scheduled for this week has been cancelled. *YNiC User Inductions* If you are aware of any new students/staff that will require access to YNiC and/or an IT account, they must attend a YNiC user induction. Our next induction will be on *Friday the 5th of May, at 13:00*. Please ask them to contact support(a)ynic.york.ac.uk to sign up. *Level 0 operator training* *The next L0 training session will be held on Monday the 22nd of May, 13:00-15:00. * Please note that users requesting Level 0 training should be a PhD, RA/Postdoc, or staff, and should already have a project proposal submitted to YNiC. Please email support(a)ynic.york.ac.uk if you have any questions or wish to book on to this session. Please note that sessions are limited to 4 trainees, which will be allocated on a first-come first-served basis. Training must be booked at least a week before the session date, in order to reserve the scanner booking. *YNiC Seminar* Unfortunately the seminar scheduled for this Thursday has been *cancelled*. Our next seminar therefore will be *Thursday the 11th of May at 4pm*, with a talk from *Dr Tirso Gonzalez*. Many thanks, Jennifer -- Jennifer Ashton, PhD Senior Research Technician York Neuroimaging Centre Working days: Monday, Tuesday and Wednesday

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YNiC Seminar - Tomorrow at midday
by Rebecca Lowndes 20 Apr '23

20 Apr '23

Hi all, Don't forget we have a YNiC seminar by *Dr Aidan Horner *titled "*Neural mechanisms of episodic binding and recollection - fMRI, MEG, and iEEG**" *tomorrow (Friday) at midday. Refreshments will be available for those attending in person at YNiC. You can also use the following link to catch the seminar on zoom https://york-ac-uk.zoom .us/j/96762553290?pwd=UEluT1lMd3V5azY5YzNmWkJCV1VTdz09 <https://www.google.com/url?q=https://york-ac-uk.zoom.us/j/96762553290?pwd%3…> See you there! Becky -- Rebecca Lowndes Research Technician York Neuroimaging Centre

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This Week at YNiC
by Jennifer Ashton 17 Apr '23

17 Apr '23

Hello, Please find details regarding upcoming inductions and training. We also have our monthly YNiC seminar *this* *Friday *(see below for details!). *YNiC User Inductions* If you are aware of any new students/staff that will require access to YNiC and/or an IT account, they must attend a YNiC user induction. Our next induction will be on *Friday the 5th of May, at 13:00*. Please ask them to contact support(a)ynic.york.ac.uk to sign up. *Level 0 operator training* *The next L0 training session will be held on Wednesday the 3rd of May, 11:00-12:00. * Please note that users requesting Level 0 training should be a PhD, RA/Postdoc, or staff, and should already have a project proposal submitted to YNiC. Please email support(a)ynic.york.ac.uk if you have any questions or wish to book on to this session. Please note that sessions are limited to 4 trainees, which will be allocated on a first-come first-served basis. Training must be booked at least a week before the session date, in order to reserve the scanner booking. *Seminar* The next YNiC seminar will be on *Friday* (21st of April) at *12pm* with a talk from *Dr Aidan Horner *titled "*Neural mechanisms of episodic binding and recollection - fMRI, MEG, and iEEG**"*. Refreshments will be available for those attending in person at YNiC, or you can use the following link to catch the seminar on zoom https://york-ac-uk.zoom .us/j/96762553290?pwd=UEluT1lMd3V5azY5YzNmWkJCV1VTdz09 <https://www.google.com/url?q=https://york-ac-uk.zoom.us/j/96762553290?pwd%3…> Have a great week! :) Many thanks, Jennifer -- Jennifer Ashton, PhD Senior Research Technician York Neuroimaging Centre Working days: Monday, Tuesday and Wednesday

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This Week at YNiC
by Jennifer Ashton 12 Apr '23

12 Apr '23

Hello, Please find details about upcoming inductions and training below. *YNiC User Inductions* If you are aware of any new students/staff that will require access to YNiC and/or an IT account, they must attend a YNiC user induction. Our next induction will be on *Friday the 5th of May, at 13:00*. Please ask them to contact support(a)ynic.york.ac.uk to sign up. *Level 0 operator training* *The next L0 training session will be held on Wednesday the 3rd of May, 11:00-12:00. * Please note that users requesting Level 0 training should be a PhD, RA/Postdoc, or staff, and should already have a project proposal submitted to YNiC. Please email support(a)ynic.york.ac.uk if you have any questions or wish to book on to this session. Please note that sessions are limited to 4 trainees, which will be allocated on a first-come first-served basis. Training must be booked at least a week before the session date, in order to reserve the scanner booking. Many thanks, Jennifer -- Jennifer Ashton, PhD Senior Research Technician York Neuroimaging Centre Working days: Monday, Tuesday and Wednesday

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YNiC Systems Maintenance - Thursday 6th April - completed
by Joe Lyons 06 Apr '23

06 Apr '23

Hello The systems maintenance has been completed and all services should be back to normal. Please email support(a)ynic.york.ac.uk is you have any problems. Happy Easter! Joe Joe Lyons, Systems Administrator York Neuroimaging Centre (YNiC), University of York joe.lyons(a)ynic.york.ac.uk 01904 435343 | 01904 326818

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Reminder: YNiC Systems Maintenance - Thursday 6th April
by Joe Lyons 05 Apr '23

05 Apr '23

Hello Just a reminder that YNiC will be closed tomorrow (Thursday 6th April) for systems patching. We'll be taking for storage offline for updates so remote desktops, cluster and booking systems etc will be unavailable. An update will be sent out once patching has been completed. Thanks Joe Joe Lyons, Systems Administrator York Neuroimaging Centre (YNiC), University of York joe.lyons(a)ynic.york.ac.uk 01904 435343 | 01904 326818

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