- ynic-users

FW: [NLC2010] Two postdoctoral positions (fMRI, MEG) and RA/Lab Manager position; University of Trento, Italy.
by Ekaterini Klepousniotou 22 Sep '10

22 Sep '10

FYI ****************************************************************** Dr. Ekaterini Klepousniotou Lecturer in Cognitive Neuroscience & Neuropsychology Institute of Psychological Sciences University of Leeds Leeds LS2 9JT UK Tel: +44 (0)113 3435716 Fax: +44 (0)113 3435749 ________________________________ From: nlc_distribution-bounces(a)nlc2009.angularis.org [nlc_distribution-bounces(a)nlc2009.angularis.org] On Behalf Of Uri Hasson [uhasson(a)gmail.com] Sent: 22 September 2010 07:00 To: nlc_distribution(a)nlc2009.angularis.org Subject: [NLC2010] Two postdoctoral positions (fMRI, MEG) and RA/Lab Manager position; University of Trento, Italy. Dear all: Applications are invited for two postdoctoral positions and one RA/Lab-manager position funded by an ERC (European Research Council) Starting Grant (PI: Uri Hasson; http://www.hasson.org). Individuals of all nationalities are encouraged to apply. Inquiries can be addressed to uri.hasson(a)unitn.it<mailto:uri.hasson@unitn.it>, and meetings can be arranged at the Neurobiology of Language Conference. Application forms will be posted at http://bit.ly/bntHrv within 14 days. The 4-year project examines the cognitive mechanisms and neural systems by which the human brain codes the recent past and predicts the immediate future. It uses neuroimaging, behavioral studies, and eye tracking methods. The ideal candidates are highly motivated and creative individuals, capable of working independently and in groups, who will thrive in a dynamic startup-like work environment. Experience with computational modeling of complex systems is helpful, as is prior work on neuroimaging of syntax/semantics. The research takes place at the Center for Mind/Brain Sciences at the University of Trento, located in the autonomous region of Trentino in Northern Italy. Salaries are comparable to those offered by research institutions in the US and Europe, include benefits and health insurance, and are commensurate with training and experience. Expected starting date for all positions is Jan 1st, 2011. Positions offered: a. Postdoctoral position (2-4 years) for fMRI research. The person will be responsible for the design of several fMRI studies, conducting data analysis and leading the write-up of scientific work. The person will have access to the center’s onsite 4T fMRI scanner. REQUIREMENTS: expertise with fMRI design and analysis methods and a solid background in cognitive neuroscience. HELPFUL: knowledge of functional connectivity methods including those applicable to resting state data, analysis of perfusion (ASL) data, R/Matlab programming, good understanding of UNIX. Interest in MEG methods. b. Postdoctoral position (2-4 years) for Magnetoencephalography (MEG) research. The person will be responsible for the design of several MEG studies, conducting data analysis and leading the write-up of scientific work. The person will have access to the center’s onsite MEG apparatus and 4T fMRI scanner. REQUIREMENTS: expertise with MEG techniques and a solid background in cognitive neuroscience. HELPFUL: Knowledge of coherence analysis and pattern classifier methods; knowledge of fMRI analysis techniques and the integration of fMRI and MEG data. C. Research Assistant/ Lab Manager. A 2-year position is available. The individual will be responsible for analysis of fMRI datasets, programming and conducting fMRI studies, and monitoring computer hardware. This position is ideal for recent college graduates considering future graduate study in cognitive neuroscience. REQUIREMENTS: Experience with fMRI analysis and good knowledge of Italian. HELPFUL: a bachelor's degree in psychology, cognitive science, neuroscience, or computer science. Experience with diverse computing environments (Linux/OSX/Windows), programming (python/perl/shell scripting, or R) and relational databases. About the University of Trento: In 2009, The University of Trento ranked first in the Italian national ranking published by the Italian Ministry of Education. The ranking is based on the quality of the research and teaching activities, as well as the success in attracting funds from the European Commission, awarded for international research projects.

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Old news?
by Philip Quinlan 21 Sep '10

21 Sep '10

PsychoPy: “PsychoPy is an open-source application to allow the presentation of stimuli and collection of data for a wide range of neuroscience, psychology and psychophysics experiments. It’s a free, powerful alternative to Presentation™ or e-Prime™ . It’s written in Python (a free alternative to Matlab™ )”. http://www.psychopy.org/ ******************************************************************** Philip Quinlan E-Mail: ptq1(a)york.ac.uk Department of Psychology FAX: (01904) 433181 The University of York Tel: (01904) 430000 Ext. 3135 Heslington Direct : (01904) 433135 York YO10 5DD U.K. ********************************************************************

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Last call
by Antony Morland 21 Sep '10

21 Sep '10

Hi Everyone, The visit by the Times Higher Education judging panel will commence at 4pm at YNiC. Pleas come and show your support..... Thanks Tony

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YNiC Visit
by Antony Morland 20 Sep '10

20 Sep '10

Dear All, Apparently, we are in the running for THE University of the Year. The folks who make the decision are visiting YNiC tomorrow. To make a good impression on them, I'd value the presence of those who are or have been engaged in neuroimaging research at YNiC. The tour of YNiC starts at 4pm and should finish at 4:30pm. Apologies for cross postings. Thanks Tony

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YNiC seminar today
by Rebecca E Millman 16 Sep '10

16 Sep '10

Dear Users Today (4-5 pm YNiC open plan) Miriam Johnson from the Hull York Medical School will give a talk on "Magnetoencephalography appearances in breathless patients with and without air flow directed to the face." Everyone is welcome to attend. Best wishes Rebecca Background: Intractable breathlessness is a common and devastating consequence of many diseases. Breathlessness affects all aspects of life, causing major distress for both patient and caregiver. Many patients face psychological, social and physical repercussions of persistent breathlessness, which require, long-term NHS support especially out of hours. Research into possible mechanisms for the perception of breathlessness has largely concentrated on peripheral pathways. However there is a growing interest in functional brain imaging using positron electron tomography scanning and functional MRI (fMRI), mainly in induced breathlessness in healthy volunteers. Similarities with pain perception are striking. However, little is known of these processes in patients with chronic breathlessness due to lung disease, indeed, one study suggests that patients with asthma demonstrate habituation and down-regulation of perceived unpleasantness due to breathlessness. Moreover we know nothing of the effect of interventions to improve breathlessness; patients with chronic breathlessness tolerate fMRI poorly. Magnetoencephalography (MEG) scanning is a possibly tolerated method but has not been tried. There is some clinical evidence that the use of a handheld fan reduces the sensation of breathlessness and may reduce the need for nebulisers and oxygen. The fan directs airflow to the area innervated by the 2nd and 3rd branches of the trigeminal nerve. It is universally available, cheap, non-invasive and easy to use in any setting alongside any other breathlessness intervention with no contra-indications. As the cost to the NHS of oxygen, nebulisers and inhalers and hospital admission are considerable, this area warrants research both with regard to clinical effect but also to mechanism of action. -- Dr. Rebecca E. Millman York Neuroimaging Centre The Biocentre York Science Park York YO10 5DG Email: rem(a)ynic.york.ac.uk Tel: 01904 435 5373

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Re: BET settings
by Chris Racey 15 Sep '10

15 Sep '10

I ran 3 identical first level FSL analyses of a localiser scan in order to compare the different bet settings (applied to all structural and functional images). I can confirm that BET with the recursive flag (-R) produces the best outcomes with higher Z values when transformed to standard space. The -B option looks good when examining the resulting BET images, and deals nicely with residual neck artefacts, but actually produces worse results at the level of the statistics. Below are images showing zstats from each first level analysis (face-place localiser), converted to standard space and displayed on the MNI brain. PPA (blue), FFA (orange), standard space - BET with no options http://i.imgur.com/q3FdX.png PPA (blue), FFA (orange), standard space - BET with -B option http://i.imgur.com/QC9al.png PPA (blue), FFA (orange), standard space - BET with recursive option (-R) http://i.imgur.com/Nqob1.png Activation is more extensive and more significant with the -R option. Images of the structural scans after each bet extraction can be seen in the album below http://laserdragon.imgur.com/brainimaging It seems that the standard pipeline involves using the -R option anyway, but I thought people might be interested to see the difference it makes, and that the -B option turns out to be pretty bad. Chris

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Re: BET settings
by Mark Hymers 13 Sep '10

13 Sep '10

On Mon, 13, Sep, 2010 at 05:53:51PM +0100, Chris Racey spoke thus.. > Actually, after my last message, Padraig came to see me and mentioned > another option -R which iteratively repeats the BET procedure from different > starting points. He suggested that this may achieve the same improved > result. I tried this option instead and indeed it does still seem to be an > improvement. However it runs considerably quicker and doesn't seem to result > in intensity changes in the image. That was going to be my suggestion too. I don't now normally run bet without using the -R flag. As Andre says, changing the starting co-ords can also help - for the record, the standard automatic cleanup for the structural scans currently uses -c 90 116 166 but doesn't use -R. I'm not entirely sure why it doesn't as I thought it did (and was about to say it did until I double checked). I'll probably change this to use -R by default (for the automatic ones) unless someone can remind me why it doesn't... Mark -- Mark Hymers York Neuroimaging Centre

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Re: BET settings
by Andre Gouws 13 Sep '10

13 Sep '10

the -c option flag too can be useful and has virtually no cost .. this simple sets the centre of gravity to which the initial sphere is fitted. find the coordinates of the AC in your participant (slice numbers) set the -c flag to this and usually the initial extraction is vastly improved. Andre' Chris Racey wrote: > Thanks Tony, > > That's a good point, I will be in a position to do this comparison in the > next day or so, after the analysis I'm running finishes. > > Actually, after my last message, Padraig came to see me and mentioned > another option -R which iteratively repeats the BET procedure from different > starting points. He suggested that this may achieve the same improved > result. I tried this option instead and indeed it does still seem to be an > improvement. However it runs considerably quicker and doesn't seem to result > in intensity changes in the image. > > I will investigate the results of these procedures on statistical outcomes > and post a comparison in the next couple of days. > > Chris > > -----Original Message----- > From: ynic-users-bounces(a)ynic.york.ac.uk > [mailto:ynic-users-bounces@ynic.york.ac.uk] On Behalf Of > am501(a)psych.york.ac.uk > Sent: 13 September 2010 17:43 > To: Chris Racey > Cc: ynic-users(a)ynic.york.ac.uk > Subject: Re: BET settings > > Thanks for this Chris. Have you any side by side fMRI analysis with and > without the -B option? Ti would be interesting to see whether or the > results of statistical treatments change and in what way. > > Tony > >> Hi all, >> >> >> >> I was having some problems bet extracting some of my structural scans, I >> was >> getting a lot of left over neck that was screwing up the alignment. I >> noticed the current version of bet has a new option flag (to me at least), >> which focuses on cleaning up the neck. >> >> >> >> The option is -B . When using this flag the processing takes considerably >> longer, something along the lines of 10-15 mins per scan. However, not >> only >> did it resolve the issue, but the resulting image looks cleaner and more >> precise than I would expect from a normal bet. I've attached a comparison >> image so you can see the effect. >> >> >> >> I did similar comparisons running this flag with functional data and it >> also >> shows improvements. At the moment I'm re-processing my data files in this >> way before running my analysis. >> >> >> >> I thought I'd mention this in case it might be a useful option for other >> people to use, but also in case anyone knows any reason why it might be >> problematic. I'd be keen to know if anyone knows of any reason why I >> shouldn't use it? I notice the overall intensity seems slightly lower when >> this flag has been used, is this likely to be a problem? >> >> >> >> Cheers, >> >> Chris Racey >> >> -- >> ynic-users mailing list >> ynic-users(a)ynic.york.ac.uk >> https://www.ynic.york.ac.uk/mailman/listinfo/ynic-users >> > > > > -- > ynic-users mailing list > ynic-users(a)ynic.york.ac.uk > https://www.ynic.york.ac.uk/mailman/listinfo/ynic-users > > > -- > ynic-users mailing list > ynic-users(a)ynic.york.ac.uk > https://www.ynic.york.ac.uk/mailman/listinfo/ynic-users -- Andre' ************************************************************************ Andre Gouws York Neuroimaging Centre The Biocentre York Science Park Heslington YO10 5DG Tel: +44 (0) 1904 435327 Fax: +44 (0) 1904 435356

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Re: BET settings
by am501＠psych.york.ac.uk 13 Sep '10

13 Sep '10

Thanks for this Chris. Have you any side by side fMRI analysis with and without the -B option? Ti would be interesting to see whether or the results of statistical treatments change and in what way. Tony > Hi all, > > > > I was having some problems bet extracting some of my structural scans, I > was > getting a lot of left over neck that was screwing up the alignment. I > noticed the current version of bet has a new option flag (to me at least), > which focuses on cleaning up the neck. > > > > The option is -B . When using this flag the processing takes considerably > longer, something along the lines of 10-15 mins per scan. However, not > only > did it resolve the issue, but the resulting image looks cleaner and more > precise than I would expect from a normal bet. I've attached a comparison > image so you can see the effect. > > > > I did similar comparisons running this flag with functional data and it > also > shows improvements. At the moment I'm re-processing my data files in this > way before running my analysis. > > > > I thought I'd mention this in case it might be a useful option for other > people to use, but also in case anyone knows any reason why it might be > problematic. I'd be keen to know if anyone knows of any reason why I > shouldn't use it? I notice the overall intensity seems slightly lower when > this flag has been used, is this likely to be a problem? > > > > Cheers, > > Chris Racey > > -- > ynic-users mailing list > ynic-users(a)ynic.york.ac.uk > https://www.ynic.york.ac.uk/mailman/listinfo/ynic-users >

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BET settings
by Chris Racey 13 Sep '10

13 Sep '10

Hi all, I was having some problems bet extracting some of my structural scans, I was getting a lot of left over neck that was screwing up the alignment. I noticed the current version of bet has a new option flag (to me at least), which focuses on cleaning up the neck. The option is -B . When using this flag the processing takes considerably longer, something along the lines of 10-15 mins per scan. However, not only did it resolve the issue, but the resulting image looks cleaner and more precise than I would expect from a normal bet. I've attached a comparison image so you can see the effect. I did similar comparisons running this flag with functional data and it also shows improvements. At the moment I'm re-processing my data files in this way before running my analysis. I thought I'd mention this in case it might be a useful option for other people to use, but also in case anyone knows any reason why it might be problematic. I'd be keen to know if anyone knows of any reason why I shouldn't use it? I notice the overall intensity seems slightly lower when this flag has been used, is this likely to be a problem? Cheers, Chris Racey

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YNiC seminar 16th September
by rem 13 Sep '10

13 Sep '10

Dear Users This week (4-5 pm YNiC open plan) Miriam Johnson from the Hull York Medical School will give a talk on "Magnetoencephalography appearances in breathless patients with and without air flow directed to the face." Everyone is welcome to attend. Best wishes Rebecca Background: Intractable breathlessness is a common and devastating consequence of many diseases. Breathlessness affects all aspects of life, causing major distress for both patient and caregiver. Many patients face psychological, social and physical repercussions of persistent breathlessness, which require, long-term NHS support especially out of hours. Research into possible mechanisms for the perception of breathlessness has largely concentrated on peripheral pathways. However there is a growing interest in functional brain imaging using positron electron tomography scanning and functional MRI (fMRI), mainly in induced breathlessness in healthy volunteers. Similarities with pain perception are striking. However, little is known of these processes in patients with chronic breathlessness due to lung disease, indeed, one study suggests that patients with asthma demonstrate habituation and down-regulation of perceived unpleasantness due to breathlessness. Moreover we know nothing of the effect of interventions to improve breathlessness; patients with chronic breathlessness tolerate fMRI poorly. Magnetoencephalography (MEG) scanning is a possibly tolerated method but has not been tried. There is some clinical evidence that the use of a handheld fan reduces the sensation of breathlessness and may reduce the need for nebulisers and oxygen. The fan directs airflow to the area innervated by the 2nd and 3rd branches of the trigeminal nerve. It is universally available, cheap, non-invasive and easy to use in any setting alongside any other breathlessness intervention with no contra-indications. As the cost to the NHS of oxygen, nebulisers and inhalers and hospital admission are considerable, this area warrants research both with regard to clinical effect but also to mechanism of action. -- ************************************************************************ Dr. Rebecca E. Millman Science Liaison Officer York Neuroimaging Centre The Biocentre York Science Park Heslington YO10 5DG Tel: +44 (0) 1904 567614 Fax: +44 (0) 1904 435356

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FW: [NLC2009] Postdoctoral and graduate RA positions University of Oxford
by Ekaterini Klepousniotou 07 Sep '10

07 Sep '10

FYI **************************************************************** Dr. Ekaterini Klepousniotou Lecturer in Cognitive Neuroscience & Neuropsychology Institute of Psychological Sciences University of Leeds Leeds LS2 9JT UK Tel: +44 (0)113 3435716 Fax: +44 (0)113 3435749 From: nlc_distribution-bounces(a)nlc2009.angularis.org [mailto:nlc_distribution-bounces@nlc2009.angularis.org] On Behalf Of Kate Watkins Sent: 07 September 2010 10:01 To: nlc_distribution(a)nlc2009.angularis.org Subject: [NLC2009] Postdoctoral and graduate RA positions University of Oxford We are advertising two jobs (one graduate research assistant and one postdoctoral researcher) in the Speech and Brain Research Group ((http://www.fmrib.ox.ac.uk/speech-and-brain) at the University of Oxford - Department of Experimental Psychology and FMRIB Centre. The research will investigate interactions between auditory and motor areas in the brain during speech perception and production. The project will employ a variety of techniques either separately or in combination; these include behavioural measures, TMS, MEG and functional MRI. Both positions are funded from 1 January 2011 for two years in the first instance with the possibility of renewal. Initial scientific enquiries about the post or the project may be directed to Dr Kate Watkins (email: kate.watkins(a)psy.ox.ac.uk<mailto:kate.watkins@psy.ox.ac.uk>) or Dr Riikka Mottonen (email: riikka.mottonen(a)psy.ox.ac.uk<mailto:riikka.mottonen@psy.ox.ac.uk>). Further particulars, including instructions on applying for these posts and a copy of the application form, are available from the Administration Offices (email: applications(a)psy.ox.ac.uk) or can be accessed on the departmental website at http://www.psy.ox.ac.uk/. The closing date for applications is 12 noon on 8 October 2010. Please quote reference number CQ/10/013 (postdoc) CQ/10/014 (graduate) on all correspondence. Interviews are scheduled for the end of October 2010. Kate Watkins, PhD University Lecturer in Department of Experimental Psychology South Parks Road, Oxford, OX1 3UD Tel: +44 (0)1865 271314 / 222581 http://www.fmrib.ox.ac.uk/speech-and-brain

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RE : Seminar today at 2pm
by Gary Green 02 Sep '10

02 Sep '10

Dear Colleagues Today, Professor Shoogo Ueno from Japan will be giving the IEEE Magnetics Society Distinguished Lecturers seminar in York. The title is "Biomagnetics: An Interdisciplinary Field Where Magnetics, Biology, and Medicine Overlap" Professor Ueno writes.. This lecture focuses on the advances in biomagnetics and bioimaging obtained mostly in our laboratory in recent years. The lecture describes: (1) a method of localized magnetic stimulation of the human brain by TMS with a figure-eight coil; (2) magneto- encephalography (MEG) to measure extremely weak magnetic fields produced from brain electrical activity using superconducting quantum interference device (SQUID) systems; (3) impedance MRI and current MRI; (4) cancer therapy and control of iron-ion release from, and uptake into, ferritin, an iron-storage protein, by using both high frequency and pulsed magnetic fields and magnetic nanoparticles; and (5) magnetic control of biological cell orientation and cell growth by strong static magnetic fields. These new biomagnetic approaches will open new horizons in brain research, brain treatment, and regenerative medicine. The seminar will be in PX001 in the Exhibition Centre of the University, at 14:00 on the 2nd of September. All welcome -- Gary Green York Neuroimaging Centre The Biocentre York Science Park Innovation Way Heslington York YO10 5DG http://www.ynic.york.ac.uk https://www.ynic.york.ac.uk/about-us/people/ggrg tel. +44 (0) 1904 435349 PA (Richard Lee) +44 (0) 1904 435329 fax +44 (0) 1904 435356 mobile +44 (0) 788 191 3004

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Lecture next week
by Gary Green 27 Aug '10

27 Aug '10

Dear Colleagues Next week, Professor Shoogo Ueno from Japan will be giving the IEEE Magnetics Society Distinguished Lecturers seminar in York. The title is "Biomagnetics: An Interdisciplinary Field Where Magnetics, Biology, and Medicine Overlap" Professor Ueno writes.. This lecture focuses on the advances in biomagnetics and bioimaging obtained mostly in our laboratory in recent years. The lecture describes: (1) a method of localized magnetic stimulation of the human brain by TMS with a figure-eight coil; (2) magneto- encephalography (MEG) to measure extremely weak magnetic fields produced from brain electrical activity using superconducting quantum interference device (SQUID) systems; (3) impedance MRI and current MRI; (4) cancer therapy and control of iron-ion release from, and uptake into, ferritin, an iron-storage protein, by using both high frequency and pulsed magnetic fields and magnetic nanoparticles; and (5) magnetic control of biological cell orientation and cell growth by strong static magnetic fields. These new biomagnetic approaches will open new horizons in brain research, brain treatment, and regenerative medicine. details of the talk and a short biography of Professor Ueno are in the attachment to this email The seminar will be in PX001 in the Exhibition Centre of the University, at 14:00 on the 2nd of September. All welcome -- Gary Green York Neuroimaging Centre The Biocentre York Science Park Innovation Way Heslington York YO10 5DG http://www.ynic.york.ac.uk https://www.ynic.york.ac.uk/about-us/people/ggrg tel. +44 (0) 1904 435349 PA (Richard Lee) +44 (0) 1904 435329 fax +44 (0) 1904 435356 mobile +44 (0) 788 191 3004

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Early onset?
by Philip Quinlan 27 Aug '10

27 Aug '10

We recently carried out an MRI study and (to keep it simple) we compared two conditions A and B. We found two regions that preferred A to B, region 1 and 2, respectively. I was keen to explore the time series a little further. So what I did was take the A-B difference for each subject in each of the regions and compute the 95%CI for each 2 sec interval from the start of the stimulus presentation. We get a difference time series for each region and for each point we have a 95%CI. I have plotted the CIs for each point on each function (one for region 1 and one for region 2). Now I note at which time point the CIs reflect a sig diff (i.e., dont cross the x axis) and what I find is that the critical difference occurs earlier for region 1 than 2. At last a window on the time course of psychological functioning? I, of course, now want to claim my Nobel Prize but suspect this is completely flawed. Please advise. Philip. ******************************************************************** Philip Quinlan E-Mail: ptq1(a)york.ac.uk Department of Psychology FAX: (01904) 433181 The University of York Tel: (01904) 430000 Ext. 3135 Heslington Direct : (01904) 433135 York YO10 5DD U.K. ********************************************************************

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book on loan
by Gary Green 13 Aug '10

13 Aug '10

I would be very grateful if the person who borrowed the book on Magnetic Resonance Spectroscopy edited by Matthews could return it, thanks Gary -- Gary Green York Neuroimaging Centre The Biocentre York Science Park Innovation Way Heslington York YO10 5DG http://www.ynic.york.ac.uk https://www.ynic.york.ac.uk/about-us/people/ggrg tel. +44 (0) 1904 435349 PA (Richard Lee) +44 (0) 1904 435329 fax +44 (0) 1904 435356 mobile +44 (0) 788 191 3004

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oh dear
by Philip Quinlan 12 Aug '10

12 Aug '10

http://www.hindawi.com/journals/ijmms/2010/769780.html ******************************************************************** Philip Quinlan E-Mail: ptq1(a)york.ac.uk Department of Psychology FAX: (01904) 433181 The University of York Tel: (01904) 430000 Ext. 3135 Heslington Direct : (01904) 433135 York YO10 5DD U.K. ********************************************************************

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birthday cakes
by Richard Lee 11 Aug '10

11 Aug '10

Birthday cakes in open plan, help yourself Richard

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Today in YNiC
by Gary Green 29 Jul '10

29 Jul '10

There is an additional seminar today At 2pm There will be a talk entitled "NMR and MRI sensitivity enhancement by Parahydrogen Induced Polarization" by Kerstin Münnemann Max Planck Institute for Polymer Research, Mainz, Germany Despite its wide applicability in chemistry, biology and medicine, Nuclear Magnetic Resonance (NMR) spectroscopy still suffers from its inherently low sensitivity. Exploiting the large signal enhancements associated with hyperpolarization techniques, such as Parahydrogen Induced Polarization (PHIP), however, NMR or MRI qualify for monitoring dynamic processes in real time. In this lecture, the synthesis and hyperpolarization of several biocompatible molecules like barbiturates, Vinylpyrrolinidon (blood plasma expander) or Dimethylcarboxylat (precursor to fumarate) will be presented. Polarization transfer to 13C in these molecules by using adequate pulse sequences is demonstrated. Moreover, constant NMR signal enhancement of 1H and 13C is shown using a continuous delivery of parahydrogen by hollow fiber membranes. This allows the acquisition of two-dimensional NMR experiments requiring multiple excitations with constant initial polarization. The membrane technique can be easily extended to produce a continuous flow of a hyperpolarized liquid as will be shown for MRI applications. All welcome

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(no subject)
by Rebecca E Millman 29 Jul '10

29 Jul '10

Dear Users Dear Users Today (4-5 pm YNiC open plan) Matt Brookes from the University of Nottingham will give a talk on "Brain network measurements using MEG and ultra-high field MRI". http://www.nottingham.ac.uk/neuroscience/contact/a-z/A-F/brookes_matt.phtml Everyone is welcome to attend. Best wishes Rebecca -- Dr. Rebecca E. Millman York Neuroimaging Centre The Biocentre York Science Park York YO10 5DG Email: rem(a)ynic.york.ac.uk Tel: 01904 435 5373

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[Fwd: [SPM] Postdoc Position at CBU, Cambridge, UK]
by Gary Green 27 Jul '10

27 Jul '10

FYI ----------- *MRC Cognition and Brain Sciences Unit -- Cambridge* *Neuroimaging Methods Post to Study Ageing* The MRC Cognition and Brain Sciences Unit is an internationally renowned research institute with state-of-the-art cognitive neuroscience facilities, including Siemens 3T MRI and 306-channel Elekta-Neuromag MEG scanners. A 2 year post-doctoral position is available to support the newly-established Cambridge Centre for Ageing and Neuroscience (CamCAN), funded by the UK BBSRC in order to relate changes in the brain with changes in cognitive function across the adult lifespan. You will be part of a Cambridge-wide collaboration, working to develop and maintain the storage and analysis pipelines for large quantities of MRI, fMRI and MEG data. This post will be available from January 2011. You will have a PhD in neuroscience, scientific computing or a related area, plus experience of analysis of neuroimaging data, such as MRI, fMRI and/or MEG. You should have excellent IT skills, being familiar with Linux and Matlab, and ideally with specialised neuroimaging analysis software. Experience of studying changes in the brain with ageing, and of cognitive neuroscience would be an advantage. You will be thorough, efficient, effective, a good communicator, and enjoy working as part of a diverse and energetic team. The starting salary will be in the range of £26,022 - £31,758 depending upon qualifications and experience. We offer a flexible pay and reward policy, 30 days annual leave entitlement, and an optional MRC final salary Pension Scheme. On site car and cycle parking is available. For informal discussion please contact Drs Rhodri Cusack or Rik Henson by email: _rhodri.cusack(a)mrc-cbu.cam.ac.uk_ <mailto:rhodri.cusack@mrc-cbu.cam.ac.uk>/_rik.henson(a)mrc-cbu.cam.ac.uk_ <mailto:rik.henson@mrc-cbu.cam.ac.uk>. Applications for this role must be made on line at _http://jobs.mrc.ac.uk_ <http://jobs.mrc.ac.uk/>. If you do not have internet access or experience technical difficulties, please contact 01793 867162, quoting reference* CBSU10/338*. If you would like to receive this advert in large print, Braille, audio, or electronic format/ hard copy, please contact the Recruitment team at the MRC Shared Service Centre on the telephone number above or _recruitment(a)ssc.mrc.ac.uk_ <mailto:recruitment@ssc.mrc.ac.uk> *Closing Date: 20**^th ** August 2010* The Medical Research Council is an Equal Opportunities Employer. ------------------------------------------------------- Dr Richard Henson Assistant Director, Neuroimaging MRC Cognition & Brain Sciences Unit 15 Chaucer Road Cambridge, CB2 7EF, UK Office: +44 (0)1223 355 294 x522 Mob: +44 (0)794 1377 345 Fax: +44 (0)1223 359 062 http://www.mrc-cbu.cam.ac.uk/people/rik.henson/personal -------------------------------------------------------

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Matlab versions
by Mark Hymers 27 Jul '10

27 Jul '10

Hi, As I mentioned a while back, just before the start of next term (September 2010) we'll change the default Matlab version to R2010a (7.10). This is just a reminder that it would be helpful if people could quickly check that any extra toolboxes or scripts which they rely on still work under 7.10 and let me know of any problems they see. If we don't get any reports, we'll assume that it's all ok. R2009a (7.8) will still be available until September 2011 as shown at: https://www.ynic.york.ac.uk/doc/ITPages/FAQ/Misc/SupportedVersions#Matlab Thank you, Mark -- Mark Hymers York Neuroimaging Centre

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YNiC seminar 29th July
by Rebecca E Millman 26 Jul '10

26 Jul '10

Dear Users This week (4-5 pm YNiC open plan) Matt Brookes from the University of Nottingham will give a talk on "Brain network measurements using MEG and ultra-high field MRI". http://www.nottingham.ac.uk/neuroscience/contact/a-z/A-F/brookes_matt.phtml Everyone is welcome to attend. Best wishes Rebecca -- ************************************************************************ Dr. Rebecca E. Millman Science Liaison Officer York Neuroimaging Centre The Biocentre York Science Park Heslington YO10 5DG Tel: +44 (0) 1904 567614 Fax: +44 (0) 1904 435356

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Seminar next week
by Gary Green 23 Jul '10

23 Jul '10

Apologies for cross-posting this to people in several email lists Next week we have two seminars on Thursday the 29th in the YNiC Open Plan area. At 2pm There will be a talk entitled "NMR and MRI sensitivity enhancement by Parahydrogen Induced Polarization" by Kerstin Münnemann Max Planck Institute for Polymer Research, Mainz, Germany Despite its wide applicability in chemistry, biology and medicine, Nuclear Magnetic Resonance (NMR) spectroscopy still suffers from its inherently low sensitivity. Exploiting the large signal enhancements associated with hyperpolarization techniques, such as Parahydrogen Induced Polarization (PHIP), however, NMR or MRI qualify for monitoring dynamic processes in real time. In this lecture, the synthesis and hyperpolarization of several biocompatible molecules like barbiturates, Vinylpyrrolinidon (blood plasma expander) or Dimethylcarboxylat (precursor to fumarate) will be presented. Polarization transfer to 13C in these molecules by using adequate pulse sequences is demonstrated. Moreover, constant NMR signal enhancement of 1H and 13C is shown using a continuous delivery of parahydrogen by hollow fiber membranes. This allows the acquisition of two-dimensional NMR experiments requiring multiple excitations with constant initial polarization. The membrane technique can be easily extended to produce a continuous flow of a hyperpolarized liquid as will be shown for MRI applications. All are welcome A separate email will announce the 4pm talk Gary -- Gary Green York Neuroimaging Centre The Biocentre York Science Park Innovation Way Heslington York YO10 5DG http://www.ynic.york.ac.uk https://www.ynic.york.ac.uk/about-us/people/ggrg tel. +44 (0) 1904 435349 PA (Richard Lee) +44 (0) 1904 435329 fax +44 (0) 1904 435356 mobile +44 (0) 788 191 3004

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Re: Job offer
by Gary Green 21 Jul '10

21 Jul '10

Wolfgang.Kilian(a)ptb.de wrote: > More information may be found on the web > > http://www.ptb.de/de/jobsausbildung/stellen/index.php?id=1163&no_cache=1&L=… > [tt_news]=2604&tx_ttnews[backPid]=96&cHash=d8268827b6 > http://ib.ptb.de/en/org/8/81/811/ResearchTopics/Hyperpolarization.html > > > > > Best regards > > Dr. Wolfgang Kilian > Physikalisch-Technische Bundesanstalt > Abbestr. 2-12 > 10587 Berlin > > Tel.: ++49-30-3481-7952 > Fax.: ++49-30-3481-7507 > E-Mail: wolfgang.kilian(a)ptb.de

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