- ynic-users

At YNiC this week.. (including important info for MRI operators)
by Andre Gouws 31 Oct '18

31 Oct '18

There are a few things to bring to your attention this week: *Final metal screening (with the aid of a metal detector)* There will be a training session in place of the seminar tomorrow @ 4pm (Thursday the 1st of Nov). All MRI operators are invited to attend to learn our new policy on final subject metal screening and to train in the use of the metal detectors we will use to aid this final screening. Please note: * Operators already trained with the metal detector do not need to attend. * We will be temporarily suspending all operators on the database and will only reinstate operator status once this training has been completed - a register will be taken tomorrow so that is your chance to keep your operator status live. *Activity at YNiC* The MScI (m-sci) scanning has begun this week and places a significant load on YNiC operators. Further to a previous email, additional operator-covered slots have been added to the booking system to facilitate ongoing research scanning. Please note that during this period we use every opportunity to train new operators and this may mean us training an operator during your scanning session. Thanks in advance for your cooperation. Best wishes, -- André ************************************************************************ André Gouws PhD Manager of Imaging Services York Neuroimaging Centre University of York The Biocentre York Science Park Heslington YO10 5NY Tel: +44 (0) 1904 435327 Fax: +44 (0) 1904 435356

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YNiC Remote Desktop
by Joe Lyons 26 Oct '18

26 Oct '18

Hello We have a new remote desktop cluster available for existing users of the remote desktop service at YNiC. This new setup has a group of desktops and will connect you to the whichever is the least used at that time. Details on how to connect are available on the wiki, https://www.ynic.york.ac.uk/docs/ITPages/NewRemoteDesktop. If you would like to use this, please email support(a)ynic.york.ac.uk. This service is only available to Psychology staff, PhD students, Postdoctoral Researchers and PIs. Thanks Joe Joe Lyons, UNIX Systems Administrator York Neuroimaging Centre (YNiC), University of York

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MRI Operator cover on scanners for the next 5 weeks
by Andre Gouws 25 Oct '18

25 Oct '18

Hello All, We are about to start a period of scanning for MSci projects. These slots (16 hours per week) are covered by YNiC operators. In addition to the 7.5 hours we need to staff our clinical scanning, we are adding more operator covered slots (18 hours) to allow PIs to undertake their research. Given the amount of operator covered slots we are using them as level 1 training opportunities as much as possible. During this period, YNiC staff will have less time to help with other issues, so please keep that in mind. Many thanks Tony, Mark and André -- André ************************************************************************ André Gouws PhD Manager of Imaging Services York Neuroimaging Centre University of York The Biocentre York Science Park Heslington YO10 5NY Tel: +44 (0) 1904 435327 Fax: +44 (0) 1904 435356

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Care Quality Commission Inspection
by Antony Morland 08 Oct '18

08 Oct '18

Hello All, Our clinical service will be inspected on a Monday occurring in the remainder of this month or all of next month. The inspectors come without any notice. The outcome of the inspection is a rating, which, depending on the the level we achieve, will allow is continue with the service effectively. We want to be rated as highly as possible. We anticipate that the inspectors will attend between 10am and 6pm. If you are at the centre during these hours, please be aware that many of the staff here may be busy cooperating with the inspectors. It would also be very much appreciated if during your time here you could use the reception area minimally and as always recognise the needs of the patients, who will be waiting for their scan in reception. Thank you Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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TMS
by Antony Morland 05 Oct '18

05 Oct '18

Hi All, Just to let you know the TMS gear will be unavailable 10th October. Best wishes Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Reboot of remote.ynic.york.ac.uk
by Joe Lyons 04 Oct '18

04 Oct '18

Hello We're seeing some NFS issues on the remote desktop server and so will be rebooting the server at 4pm today. Please save any work and log off before this time. Thanks Joe -- Joe Lyons, UNIX Systems Administrator York Neuroimaging Centre (YNiC), University of York

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Ethics applications
by Gareth Gaskell 01 Oct '18

01 Oct '18

Dear all, just a quick reminder to anyone planning to put in a new YNiC ethics application that the forms at the full application stage have changed, including the application form, the consent form and the participant information sheet. This means that it's much better to start afresh from the templates provided here <https://www.ynic.york.ac.uk/forms> than to rework an older outdated application. For users who are new to the system, the procedure for applying to run a study at YNiC is given here <https://www.ynic.york.ac.uk/information/application>. Many thanks, Gareth YNiC REC Chair -- Gareth Gaskell Department of Psychology University of York Heslington, York YO10 5DD UK Office: Psychology, E209 Phone: +44-1904-323187 Email: gareth.gaskell(a)york.ac.uk Home page: https://www.york.ac.uk/psychology/staff/academicstaff/mgg5/ Research group: https://www.york.ac.uk/psychology/research/facilities/slam/

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YNIC Science Committee
by Jonny Smallwood 01 Oct '18

01 Oct '18

Hello The next meeting of the YSC is on the 8th of October. Please could any users that have issues they would like raised at this meeting, send them to me by the end of play on Friday? Thanks, Jonny -- Jonathan Smallwood, Reader in Psychology / Cognitive Neuroscience Room C023, Department of Psychology, University of York, England. YO10 4PH. Telephone: 01904 324651

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YNiC Project presentation Thursday 27th @ 4pm.
by Andre Gouws 26 Sep '18

26 Sep '18

Hi all, We will be hosting a project presentation by Bardur Joensen (Berens, Horner) at YNiC tomorrow (Thurs 27th) at 4pm: “ Tracking the retrieval of episodic events over time ”. Please join us for the presentation and discussion to be followed by light refreshments. Best wishes (and sorry for the late notice), -- André ************************************************************************ André Gouws PhD Manager of Imaging Services York Neuroimaging Centre University of York The Biocentre York Science Park Heslington YO10 5NY Tel: +44 (0) 1904 435327 Fax: +44 (0) 1904 435356

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GE scanner update
by Antony Morland 25 Sep '18

25 Sep '18

Hello All, I am happy to report that the GE scanner is now up and running. Best wishes Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Teaching at YNiC
by Mark Hymers 24 Sep '18

24 Sep '18

Dear all, As usual, there will be teaching in the YNiC Open plan area during the autumn and spring terms. During these times, the area will be closed to anybody not involved in the teaching. Times for the Autumn term are: Week 1: Thursday 27th September 0900-1300 Friday 28th September 0900-1300 Week 2: Tuesday 2nd October: 1200-1400 Week 4: Tuesday 16th October: 1200-1400 Week 7: Tuesday 6th November: 1200-1400 Week 9: Tuesday 20th November: 1200-1400 Times for the Spring term will be sent out during the Christmas vacation period. Thanks, Mark -- Mark Hymers, Lecturer in Neuroimaging Methods York NeuroImaging Centre and Department of Psychology University of York, UK Please note that my email address is: mark.hymers(a)ynic.york.ac.uk Responses to messages sent to other addresses may be delayed

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Upgrades and changes
by Antony Morland 24 Sep '18

24 Sep '18

Hello All, We are now open after our summer closure for upgrades and maintenance. As always, please let us know if there is anything that no longer functions as it did and we will try to rectify the situation. Here is a summary of what has been updated/upgraded during the closure: *Software*: FSLeyes upgraded to most recent version (0.26.1) Psychopy upgraded to 1.90.3 including changes to video handling (addition of moviepy and sounddevice) Matlab 9.4 added; no Matlab versions removed; 9.0 will be removed in January. Libreoffice upgraded to 6.1 Crossover Office upgraded to 17.5 Mendeley upgraded to latest release SPM 12 upgraded to latest patch (r7219) Windows is no longer supported on the Stimulus PCs *Hardware changes:*New cabling of offices Networking improvements Telephony updated New chiller installed for GE system - this should be completed by tomorrow *Estate:* The Chemistry areas have been reconfigured and rationalized Best wishes Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Email addresses
by Antony Morland 24 Sep '18

24 Sep '18

Hello All, We have received (indirectly) some emails asking for help. They were posted to rec-submission(a)ynic.york.ac This is the address to send ethics applications, not a email queue that we monitor for general issues. To avoid undue delays please send requests for help etc to support(a)ynic.york.ac.uk Many thanks Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Fwd: REMINDER - SEMINAR INFO: JEOL Postdoc Competition Winners' Seminar & refreshments, TOMORROW, 13:00, C/A/101
by Antony Morland 20 Sep '18

20 Sep '18

The second talk described below may be of interest *JEOL Postdoc Competition Winners’ Seminar * *Thursday 20th September * *13.00-15.00* *C/A101* *13.00 Dr. Aggie Lawer* *"Synthesis of functionalised peptides/macrocycles and medium-size **rings via stereoselective fluorination and SuRE/NICE chemistry"* Insertion of fluorine into organic molecules is well-known to affect the molecules’ electronic distribution and conformation in ways that can be beneficial in drug development. However, the effects of fluorination have not been widely investigated in the context of peptides, which limits the development of peptide-based drugs. In the first part of the talk, I will discuss how stereoselective fluorination was used to control the conformations of peptides and enhance the potency of a peptide-based enzyme inhibitor. While peptides/macrocycles and medium-size rings have recently gained noteworthy interest in the area of medicinal chemistry, their synthesis is mostly limited to the traditional end-to-end macrocyclisations which suffer from unfavourable thermodynamic factors, and oftentimes require the use of high dilution conditions. In the second part of my talk, I’ll describe how Successive Ring Expansion (SuRE) and N-acyl Iminium ion mediated Cyclisation/Expansion (NICE) reactions developed in Unsworth group could be employed to overcome these limitations, providing an efficient, scalable and practical route to make diverse macrocycles and medium-size rings. *13.45 Dr. Peter Rayner * *"Tunable Hyperpolarisation by Synthetic Design"* NMR and MRI are two of the most popular techniques to study molecules and materials. However, both of these approaches are insensitive and hyperpolarization methods to increase signal size are needed in order to access new applications. This talk will describe how rational synthetic design of both the contrast agents and N-heterocyclic carbene catalysts utilized in the Signal Amplification by Reversible Exchange process, have led to signals that are up to 120,000 times larger than those achieved on a typical hospital scanner and can be observed many minutes after their creation. These improvements have allowed the observation of hyperpolarized molecules by in vivo MRI techniques. *The seminar will be followed at 14.30 by refreshments* -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Remote desktop
by Antony Morland 17 Sep '18

17 Sep '18

Hello All, The Remote Desktop is now up and running. We are still closed for maintenance and upgrades so while we hope the service will run uninterrupted, there may be unplanned outages. Best wishes Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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GE update
by Antony Morland 28 Aug '18

28 Aug '18

Apologies, All, the GE scanner is down until further notice. The water chiller that we have been having difficulties with has finally given up the ghost. Plans for replacement are underway. Best wishes Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Some updates
by Antony Morland 21 Aug '18

21 Aug '18

Hello All, 1. A day for your diaries: 14th September 'YNiC Science Day' will be held in B020. More details to follow from Jonny nearer the time. 2. YNiC will be close 11th September to reopen 24th September. This will allow for our annual maintenance and upgrades to the centre. 3. As many of you may know, we had a significant period of unscheduled down time on the GE scanner. The problem has now been fixed. Best wishes Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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YNiC Science Day_September 14th_Call for existing conference posters
by Magdalena Sliwinska 20 Aug '18

20 Aug '18

Dear All, *The Science Day 2018*, held in our department, is slowly approaching us. During that day, Jonny and I would like to display posters that YNiC users, especially ECRs, have presented at conferences over the last year. If any of you have posters buried in dust in the dark corners of your offices and would like them to see a daylight again, please let us know. NOTE: It is not required to stand next to the poster, so even if you are away on that day, we can still present your awesome work to the department. I will arrange collection of your posters from you, so to make it happen just drop me an email. Many thanks, Magda -- *Magdalena W. Sliwinska, PhD* Research Associate Department of Psychology University of York Heslington, York, YO10 5DD, UK tel: 01904323177

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GE Scanner - repairs underway
by Andre Gouws 30 Jul '18

30 Jul '18

Hi all, I am afraid that the GE scanner is in need of repair that means it may be out of service for at least a week. In light of the recent UK weather patterns, you will probably not be surprised to hear that this is due to the failure of one of the water chillers. We will keep you updated with the status of the scanner. Best wishes, -- André ************************************************************************ André Gouws PhD Manager of Imaging Services York Neuroimaging Centre University of York The Biocentre York Science Park Heslington YO10 5NY Tel: +44 (0) 1904 435327 Fax: +44 (0) 1904 435356

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Seminar 26th June
by Antony Morland 23 Jul '18

23 Jul '18

Hi All, Our talk on Thursday at 4pm will be.... *Andrew Logan, Bradford University* *Title:* Quantifying impairments of face perception in age-related macular degeneration *This project aimed to develop a new method of testing face perception ability which is suitable for use in a clinical environment. Our data quantify the impact of age-related macular degeneration- the leading cause of irreversible visual impairment in the UK- on face perception; an everyday visual function with links to quality of life.* Refreshments available afterwards Best wishes -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Project presentation: Thursday 19th
by andre＠ynic.york.ac.uk 18 Jul '18

18 Jul '18

Hi all, We will be hosting a project presentation by Sara Stampacchia at YNiC tomorrow (Thurs 19th) at 4pm: “Exploring the neural substrate of control over memory representations”. Please join us for the presentation and discussion to be followed by light refreshments. Best wishes, André ************************************************************************ André Gouws PhD Manager of Imaging Services York Neuroimaging Centre University of York The Biocentre York Science Park Heslington YO10 5NY Tel: +44 (0) 1904 435327 Fax: +44 (0) 1904 435356

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Project presentation this Thursday
by Antony Morland 02 Jul '18

02 Jul '18

Hello All, Come to the air-conditioned cool at YNiC on Thursday at 4pm to hear David Pitcher talk about: 1. Mapping the functional connections of V5/MT: A combined TMS/fMRI study 2. Measuring the time line of face recognition using TMS and ERP These will be project presentations that offer everyone the chance to learn about approaches investigators using the centre employ to do their research. All welcome and refreshments will be provided. Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Removal of Windows from YNiC stimulus PCs
by Andre Gouws 29 Jun '18

29 Jun '18

Hi all, There has been a marked decrease in the usage of Windows on the YNiC provided stimulus PCs over the past 3 years. This appears to due to three main factors: 1) We no longer provide licenses for Presentation and E-Prime on our machines (Windows specific packages) 2) There has been an increase in the number of users who use their own stimulus laptops (and plug them into our projector & response box) 3) YNiC has invested heavily in getting the two most commonly used stimulus packages (PsychoPy and PsychToolbox) running efficiently on Linux. Maintaining a managed, networked Windows build for stimulus delivery use is a significant overhead for us. Due to the lack of use of the Windows build on our machines, we are *proposing to **remove Windows entirely from our stimulus PCs* during our next planned system maintenance scheduled for September 2018. This is your opportunity to *e**xpress an opinion or concern* if you have any - please send your remarks to: support(a)ynic.york.ac.uk .. with the title: Windows stimulus PCs Thanks, -- André ************************************************************************ André Gouws PhD Manager of Imaging Services York Neuroimaging Centre University of York The Biocentre York Science Park Heslington YO10 5NY Tel: +44 (0) 1904 435327 Fax: +44 (0) 1904 435356

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Fwd: Talk at YNiC 4pm tomorrow - neuroimaging and optic neuritis
by Antony Morland 21 Jun '18

21 Jun '18

Talk at 4pm today. Apologies for the late notice. ---------- Forwarded message ---------- From: Alex Wade <alex.wade(a)york.ac.uk> Date: 20 June 2018 at 22:08 Subject: Talk at YNiC 4pm tomorrow - neuroimaging and optic neuritis To: Faculty <faculty-psyc-group(a)york.ac.uk>, Researchers - Postdocs < pds-psyc-group(a)york.ac.uk> Yael Backner from the Hadassa Neuroimaging Center in Israel will be giving a talk on the neuroscience of optic neuritis: a degenerative disease related to multiple sclerosis. Yael works as part of a world-class team in Jerusalem and her talk will be excellent. YNiC. 4pm. Refreshments will be served afterwards. Best Alex -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Important: Access to MRI is limited to your booked slot only.
by Andre Gouws 14 Jun '18

14 Jun '18

(This message is relevant to operators and anyone booking the scanners). Access to the MRI facilities is *limited to the time slot you have booked* for your scanning. Do not assume that you can start 15 minutes early, over-run by 10 minutes or just pop in to test things if the scanners do not appear to be booked. The scanners are becoming increasingly busy and the demands on the team at YNiC are increasing proportionally. Efficient time management of the scanning resources and cover are more important than ever. The staff here are often doing things in the background to support the service that means they are not available to help you out at the drop of a hat. If you require extra time for setup, testing or tweaking please ensure that you book additional time. Anyone found in the scanner rooms outside their booked time slots will be invoiced for the additional time they have had access to the suites. If you have any queries please drop me a line. Best wishes, -- André ************************************************************************ André Gouws PhD Manager of Imaging Services York Neuroimaging Centre University of York The Biocentre York Science Park Heslington YO10 5NY Tel: +44 (0) 1904 435327 Fax: +44 (0) 1904 435356

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