- ynic-users

YNIC Science Committee
by Jonny Smallwood 01 Oct '18

01 Oct '18

Hello The next meeting of the YSC is on the 8th of October. Please could any users that have issues they would like raised at this meeting, send them to me by the end of play on Friday? Thanks, Jonny -- Jonathan Smallwood, Reader in Psychology / Cognitive Neuroscience Room C023, Department of Psychology, University of York, England. YO10 4PH. Telephone: 01904 324651

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YNiC Project presentation Thursday 27th @ 4pm.
by Andre Gouws 26 Sep '18

26 Sep '18

Hi all, We will be hosting a project presentation by Bardur Joensen (Berens, Horner) at YNiC tomorrow (Thurs 27th) at 4pm: “ Tracking the retrieval of episodic events over time ”. Please join us for the presentation and discussion to be followed by light refreshments. Best wishes (and sorry for the late notice), -- André ************************************************************************ André Gouws PhD Manager of Imaging Services York Neuroimaging Centre University of York The Biocentre York Science Park Heslington YO10 5NY Tel: +44 (0) 1904 435327 Fax: +44 (0) 1904 435356

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GE scanner update
by Antony Morland 25 Sep '18

25 Sep '18

Hello All, I am happy to report that the GE scanner is now up and running. Best wishes Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Teaching at YNiC
by Mark Hymers 24 Sep '18

24 Sep '18

Dear all, As usual, there will be teaching in the YNiC Open plan area during the autumn and spring terms. During these times, the area will be closed to anybody not involved in the teaching. Times for the Autumn term are: Week 1: Thursday 27th September 0900-1300 Friday 28th September 0900-1300 Week 2: Tuesday 2nd October: 1200-1400 Week 4: Tuesday 16th October: 1200-1400 Week 7: Tuesday 6th November: 1200-1400 Week 9: Tuesday 20th November: 1200-1400 Times for the Spring term will be sent out during the Christmas vacation period. Thanks, Mark -- Mark Hymers, Lecturer in Neuroimaging Methods York NeuroImaging Centre and Department of Psychology University of York, UK Please note that my email address is: mark.hymers(a)ynic.york.ac.uk Responses to messages sent to other addresses may be delayed

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Upgrades and changes
by Antony Morland 24 Sep '18

24 Sep '18

Hello All, We are now open after our summer closure for upgrades and maintenance. As always, please let us know if there is anything that no longer functions as it did and we will try to rectify the situation. Here is a summary of what has been updated/upgraded during the closure: *Software*: FSLeyes upgraded to most recent version (0.26.1) Psychopy upgraded to 1.90.3 including changes to video handling (addition of moviepy and sounddevice) Matlab 9.4 added; no Matlab versions removed; 9.0 will be removed in January. Libreoffice upgraded to 6.1 Crossover Office upgraded to 17.5 Mendeley upgraded to latest release SPM 12 upgraded to latest patch (r7219) Windows is no longer supported on the Stimulus PCs *Hardware changes:*New cabling of offices Networking improvements Telephony updated New chiller installed for GE system - this should be completed by tomorrow *Estate:* The Chemistry areas have been reconfigured and rationalized Best wishes Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Email addresses
by Antony Morland 24 Sep '18

24 Sep '18

Hello All, We have received (indirectly) some emails asking for help. They were posted to rec-submission(a)ynic.york.ac This is the address to send ethics applications, not a email queue that we monitor for general issues. To avoid undue delays please send requests for help etc to support(a)ynic.york.ac.uk Many thanks Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Fwd: REMINDER - SEMINAR INFO: JEOL Postdoc Competition Winners' Seminar & refreshments, TOMORROW, 13:00, C/A/101
by Antony Morland 20 Sep '18

20 Sep '18

The second talk described below may be of interest *JEOL Postdoc Competition Winners’ Seminar * *Thursday 20th September * *13.00-15.00* *C/A101* *13.00 Dr. Aggie Lawer* *"Synthesis of functionalised peptides/macrocycles and medium-size **rings via stereoselective fluorination and SuRE/NICE chemistry"* Insertion of fluorine into organic molecules is well-known to affect the molecules’ electronic distribution and conformation in ways that can be beneficial in drug development. However, the effects of fluorination have not been widely investigated in the context of peptides, which limits the development of peptide-based drugs. In the first part of the talk, I will discuss how stereoselective fluorination was used to control the conformations of peptides and enhance the potency of a peptide-based enzyme inhibitor. While peptides/macrocycles and medium-size rings have recently gained noteworthy interest in the area of medicinal chemistry, their synthesis is mostly limited to the traditional end-to-end macrocyclisations which suffer from unfavourable thermodynamic factors, and oftentimes require the use of high dilution conditions. In the second part of my talk, I’ll describe how Successive Ring Expansion (SuRE) and N-acyl Iminium ion mediated Cyclisation/Expansion (NICE) reactions developed in Unsworth group could be employed to overcome these limitations, providing an efficient, scalable and practical route to make diverse macrocycles and medium-size rings. *13.45 Dr. Peter Rayner * *"Tunable Hyperpolarisation by Synthetic Design"* NMR and MRI are two of the most popular techniques to study molecules and materials. However, both of these approaches are insensitive and hyperpolarization methods to increase signal size are needed in order to access new applications. This talk will describe how rational synthetic design of both the contrast agents and N-heterocyclic carbene catalysts utilized in the Signal Amplification by Reversible Exchange process, have led to signals that are up to 120,000 times larger than those achieved on a typical hospital scanner and can be observed many minutes after their creation. These improvements have allowed the observation of hyperpolarized molecules by in vivo MRI techniques. *The seminar will be followed at 14.30 by refreshments* -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Remote desktop
by Antony Morland 17 Sep '18

17 Sep '18

Hello All, The Remote Desktop is now up and running. We are still closed for maintenance and upgrades so while we hope the service will run uninterrupted, there may be unplanned outages. Best wishes Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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GE update
by Antony Morland 28 Aug '18

28 Aug '18

Apologies, All, the GE scanner is down until further notice. The water chiller that we have been having difficulties with has finally given up the ghost. Plans for replacement are underway. Best wishes Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Some updates
by Antony Morland 21 Aug '18

21 Aug '18

Hello All, 1. A day for your diaries: 14th September 'YNiC Science Day' will be held in B020. More details to follow from Jonny nearer the time. 2. YNiC will be close 11th September to reopen 24th September. This will allow for our annual maintenance and upgrades to the centre. 3. As many of you may know, we had a significant period of unscheduled down time on the GE scanner. The problem has now been fixed. Best wishes Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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YNiC Science Day_September 14th_Call for existing conference posters
by Magdalena Sliwinska 20 Aug '18

20 Aug '18

Dear All, *The Science Day 2018*, held in our department, is slowly approaching us. During that day, Jonny and I would like to display posters that YNiC users, especially ECRs, have presented at conferences over the last year. If any of you have posters buried in dust in the dark corners of your offices and would like them to see a daylight again, please let us know. NOTE: It is not required to stand next to the poster, so even if you are away on that day, we can still present your awesome work to the department. I will arrange collection of your posters from you, so to make it happen just drop me an email. Many thanks, Magda -- *Magdalena W. Sliwinska, PhD* Research Associate Department of Psychology University of York Heslington, York, YO10 5DD, UK tel: 01904323177

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GE Scanner - repairs underway
by Andre Gouws 30 Jul '18

30 Jul '18

Hi all, I am afraid that the GE scanner is in need of repair that means it may be out of service for at least a week. In light of the recent UK weather patterns, you will probably not be surprised to hear that this is due to the failure of one of the water chillers. We will keep you updated with the status of the scanner. Best wishes, -- André ************************************************************************ André Gouws PhD Manager of Imaging Services York Neuroimaging Centre University of York The Biocentre York Science Park Heslington YO10 5NY Tel: +44 (0) 1904 435327 Fax: +44 (0) 1904 435356

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Seminar 26th June
by Antony Morland 23 Jul '18

23 Jul '18

Hi All, Our talk on Thursday at 4pm will be.... *Andrew Logan, Bradford University* *Title:* Quantifying impairments of face perception in age-related macular degeneration *This project aimed to develop a new method of testing face perception ability which is suitable for use in a clinical environment. Our data quantify the impact of age-related macular degeneration- the leading cause of irreversible visual impairment in the UK- on face perception; an everyday visual function with links to quality of life.* Refreshments available afterwards Best wishes -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Project presentation: Thursday 19th
by andre＠ynic.york.ac.uk 18 Jul '18

18 Jul '18

Hi all, We will be hosting a project presentation by Sara Stampacchia at YNiC tomorrow (Thurs 19th) at 4pm: “Exploring the neural substrate of control over memory representations”. Please join us for the presentation and discussion to be followed by light refreshments. Best wishes, André ************************************************************************ André Gouws PhD Manager of Imaging Services York Neuroimaging Centre University of York The Biocentre York Science Park Heslington YO10 5NY Tel: +44 (0) 1904 435327 Fax: +44 (0) 1904 435356

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Project presentation this Thursday
by Antony Morland 02 Jul '18

02 Jul '18

Hello All, Come to the air-conditioned cool at YNiC on Thursday at 4pm to hear David Pitcher talk about: 1. Mapping the functional connections of V5/MT: A combined TMS/fMRI study 2. Measuring the time line of face recognition using TMS and ERP These will be project presentations that offer everyone the chance to learn about approaches investigators using the centre employ to do their research. All welcome and refreshments will be provided. Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Removal of Windows from YNiC stimulus PCs
by Andre Gouws 29 Jun '18

29 Jun '18

Hi all, There has been a marked decrease in the usage of Windows on the YNiC provided stimulus PCs over the past 3 years. This appears to due to three main factors: 1) We no longer provide licenses for Presentation and E-Prime on our machines (Windows specific packages) 2) There has been an increase in the number of users who use their own stimulus laptops (and plug them into our projector & response box) 3) YNiC has invested heavily in getting the two most commonly used stimulus packages (PsychoPy and PsychToolbox) running efficiently on Linux. Maintaining a managed, networked Windows build for stimulus delivery use is a significant overhead for us. Due to the lack of use of the Windows build on our machines, we are *proposing to **remove Windows entirely from our stimulus PCs* during our next planned system maintenance scheduled for September 2018. This is your opportunity to *e**xpress an opinion or concern* if you have any - please send your remarks to: support(a)ynic.york.ac.uk .. with the title: Windows stimulus PCs Thanks, -- André ************************************************************************ André Gouws PhD Manager of Imaging Services York Neuroimaging Centre University of York The Biocentre York Science Park Heslington YO10 5NY Tel: +44 (0) 1904 435327 Fax: +44 (0) 1904 435356

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Fwd: Talk at YNiC 4pm tomorrow - neuroimaging and optic neuritis
by Antony Morland 21 Jun '18

21 Jun '18

Talk at 4pm today. Apologies for the late notice. ---------- Forwarded message ---------- From: Alex Wade <alex.wade(a)york.ac.uk> Date: 20 June 2018 at 22:08 Subject: Talk at YNiC 4pm tomorrow - neuroimaging and optic neuritis To: Faculty <faculty-psyc-group(a)york.ac.uk>, Researchers - Postdocs < pds-psyc-group(a)york.ac.uk> Yael Backner from the Hadassa Neuroimaging Center in Israel will be giving a talk on the neuroscience of optic neuritis: a degenerative disease related to multiple sclerosis. Yael works as part of a world-class team in Jerusalem and her talk will be excellent. YNiC. 4pm. Refreshments will be served afterwards. Best Alex -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Important: Access to MRI is limited to your booked slot only.
by Andre Gouws 14 Jun '18

14 Jun '18

(This message is relevant to operators and anyone booking the scanners). Access to the MRI facilities is *limited to the time slot you have booked* for your scanning. Do not assume that you can start 15 minutes early, over-run by 10 minutes or just pop in to test things if the scanners do not appear to be booked. The scanners are becoming increasingly busy and the demands on the team at YNiC are increasing proportionally. Efficient time management of the scanning resources and cover are more important than ever. The staff here are often doing things in the background to support the service that means they are not available to help you out at the drop of a hat. If you require extra time for setup, testing or tweaking please ensure that you book additional time. Anyone found in the scanner rooms outside their booked time slots will be invoiced for the additional time they have had access to the suites. If you have any queries please drop me a line. Best wishes, -- André ************************************************************************ André Gouws PhD Manager of Imaging Services York Neuroimaging Centre University of York The Biocentre York Science Park Heslington YO10 5NY Tel: +44 (0) 1904 435327 Fax: +44 (0) 1904 435356

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YNIC Science Day September 14th - Presenters needed!
by Jonny Smallwood 12 Jun '18

12 Jun '18

Hello YNIC Users We are holding YNIC Science Day in B020 on September the 14th. The plan for this event is to showcase the work we are doing at YNIC to the wider community. One aspect of this event will be a series of short talks by early career researchers that describe the techniques they use in their research. Consequently, I am looking for volunteers to give short 5 minute talks about the work they are doing at the imaging centre. Please get in contact with me via email, or in person, if you have imaging data that you would like to present. Thanks Jonny -- Jonathan Smallwood, Reader in Psychology / Cognitive Neuroscience Room C023, Department of Psychology, University of York, England. YO10 4PH. Telephone: 01904 324651

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Update
by Antony Morland 12 Jun '18

12 Jun '18

Hello All, Gareth Gaskell, Chair of the YNiC Research Governance Committee, has reconfigured the YNiC Ethics application form, which is now in version 6. This form is available on the YNiC website. There is also an updated guidance document, version 4. The main changes concern GDPR, which Gareth has communicated about already. Other news; in our efforts to save the planet - one of our key missions - we are no longer going to provide paper cups for hot drinks. Please bring a reusable mug for your drinks. Best wishes Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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New YNiC ethics forms
by Gareth Gaskell 25 May '18

25 May '18

Dear YNiC users, The GDPR coming in today has entailed a modest revision of our YNiC ethics forms. The new versions (V4 of the form and V6 of the guidance) will be available on the YNiC website soon, and should be used for all new applications. The changes aren't too major - essentially Section 7 of the application form on data has been expanded to allow some extra checks to be performed on your data processing plans. One aspect that is new is that PIs need to consider whether their data might be considered "high risk" from a data protection point of view, and if this is a possibility then a Data Privacy Impact Assessment (DPIA) would need to be carried out. My reading of the definition of high risk <https://www.york.ac.uk/records-management/dp/dataprivacyimpactassessments/> is that most YNiC research wouldn't require this step. Further, if a strand of research does need an assessment then as I understand it an assessment could be carried out to cover that strand as a whole rather than each individual project. So I don't anticipate this being too burdensome in the main. At the same time there are some new statements that need to be included in the participant information sheets and consent forms, and I have taken the opportunity to try to streamline the application process so that it is less time-consuming. I have cut down the guidance notes that you need to consult in making an application, and have added a template information sheet and a template consent form that you can adapt for your purposes. As well as making the application process a bit easier to complete, I am hopeful that there is less opportunity for researchers to use wording in their information sheets that conflicts with our guidelines. I'm happy to get feedback on how well this works and whether you can see further ways to improve the process. Current projects with ethical approval do not need to be re-approved, but it would be helpful if any participant you test from now on could be given the attached supplementary information sheet as well as the information sheet that you have been using, to inform participants about their data under GDPR. Please use the new forms for any new applications. People who are currently in the process of putting together applications (e.g., for this year's MPsych projects) can either use the new forms (preferred) or stick with the old forms provided they (i) verbally agree to the new statements in Section 7 in their application email, and (ii) add the attached supplementary information sheet to their participant information sheet. Please let me know if you have questions or concerns, best, Gareth Gaskell Chair YNiC Ethics and Governance Committee -- Gareth Gaskell Department of Psychology University of York Heslington, York YO10 5DD UK Office: Psychology, E209 Phone: +44-1904-323187 Email: gareth.gaskell(a)york.ac.uk Home page: https://www.york.ac.uk/psychology/staff/academicstaff/mgg5/ Research group: https://www.york.ac.uk/psychology/research/facilities/slam/

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Updates
by Antony Morland 15 May '18

15 May '18

Hello All, We will be a little short staffed at the end of this week and next as some of our team are going to be away on leave and at conferences. All operator covered slots will be covered. We have been making some good progress testing new imaging sequences on the Siemens scanner, which later in the year should make some new experimental approaches possible for users. Best wishes Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Planned summer closure
by Antony Morland 10 May '18

10 May '18

Dear All, The centre will be closed from Tuesday, 11th September to reopen Monday, 24th September, to allow for vital annual maintenance. Best wishes Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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Changes to booking scanners
by Antony Morland 02 May '18

02 May '18

Hello All, I have had some discussions with investigators recently relating to booking scanners. There are some funded labs that have the resources and will benefit scientifically from scanning for more than seven hours per week, which is our normal upper limit. We currently have capacity on the scanners, so our limit is artificially restricting research throughput. We have decided therefore to lift the limits on booking for funded projects for a trial period until the end of the calendar year. While this will offer benefits to funded projects, it may have adverse effects on other uses of the scanners. Being mindful of that, we are (1) trialing the system and (2) asking funded projects to book the scanner responsibly. Considering the second point, could you please get in touch if you would like the limit on your funded project raised - email support(a)ynic.york.ac.uk. Also, if you do have a raised limit and wish to book intensive use of the scanners please do so with as much lead time as possible - you will have a six week window - because this will help other users plan their work. Best wishes Tony -- Antony Morland, PhD. Director, York Neuroimaging Centre Department of Psychology, University of York, York YO10 5DD, UK.

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YNIC Science Day
by Jonny Smallwood 01 May '18

01 May '18

Hello everyone, Yesterday at the YNIC Science Committee we decided to hold YNIC Science Day on Friday the 14th of September. The plan is to us the afternoon to showcase the research at YNIC and provide an overview of the methods that we are applying to understand the neural mechanisms that underpin psychological functioning. This will take place in B020. The basic idea is to hold some short talks from a wide range of PhDs and Post docs to give a snap shot of the type of studies we conduct (similar to the data blitz's that take place at conferences), as well as some more focused talks that highlight the methods that we use to understand psychological processes. For those of you interested please put this date into your diaries! I will be in touch with the ECRs to solicit people for the short talks, but if anyone is especially interested to present their research they can contact me. Jonny -- Jonathan Smallwood, Reader in Psychology / Cognitive Neuroscience Room C023, Department of Psychology, University of York, England. YO10 4PH. Telephone: 01904 324651

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