Today's seminar at 4pm in person or on zoom. Refreshments will be provided.
https://york-ac-uk.zoom
.us/j/96762553290?pwd=UEluT1lMd3V5azY5YzNmWkJCV1VTdz09
<https://www.google.com/url?q=https://york-ac-uk.zoom.us/j/96762553290?pwd%3DUEluT1lMd3V5azY5YzNmWkJCV1VTdz09&sa=D&source=calendar&ust=1681979309240863&usg=AOvVaw1V8mxn3A7UZR8fs1w-oipq>
The role of localised sleep spindles in adaptive memory consolidation
Summary:
Sleep spindles are 12-15Hz waxing and waning neural oscillations occurring
during non-rapid eye movement sleep. They are believed to be
mechanistically involved in memory consolidation, the strengthening and
stabilisation of recently acquired memories, through inducing LTP and
synaptic plasticity in learning-related hippocampal-cortical networks. A
recent framework proposes that spindle-mediated memory consolidation should
favour so-called adaptive memories, those experiences that are personally
salient or goal-relevant. In this talk, I will present an outline for a
study designed to directly test this hypothesis for the first time. I will
employ a lateralised encoding task and present stimuli to a single visual
field that should create distinct encoding representations in the
contralateral hemisphere. Memory for items in one visual field will be
prioritised for consolidation by being associated with a financial reward
if remembered at a post-sleep test. I hypothesise that during sleep, sleep
spindle activity will be heightened over the rewarded hemisphere (compared
with unrewarded), and that this spindle activity will correlate with memory
for the high-reward items.
See you all there
Becky
--
Rebecca Lowndes
Research Technician
York Neuroimaging Centre