- ynic-users

SET for Britian
by Michael Simpson 25 Nov '09

25 Nov '09

Dear Users, can I flag this up to the young, keen and eager researchers at YNiC. It's a poster competition at the House of Commons, run by the Parliamentary and Scientific Committee. I found it a very useful experience a few years ago. http://www.vmine.net/setforbritain/2010event.asp Michael

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YNiC seminar 26th November
by rem 23 Nov '09

23 Nov '09

Dear Users This Thursday (4-5 pm in YNiC open plan) there will be two project proposal presentations: 1) Silke Goebel, Department of Psychology "No brain for numbers? Parietal networks involved in number processing and arithmetic in dyslexia/dyscalculia" 2) Eytan Zweig, Department of Language and Linguistic Science "An MEG investigation of scalar implicature calculation" Everyone is welcome to attend. Best wishes Rebecca

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FW: [BIC-announce] Fwd: Post Doctoral Fellowship Position - Brain Imaging - Robarts
by Ekaterini Klepousniotou 21 Nov '09

21 Nov '09

A post-doctoral opportunity that might be of interest to some. Katerina ****************************************************************** Dr. Ekaterini Klepousniotou Lecturer in Cognitive Neuroscience & Neuropsychology Institute of Psychological Sciences University of Leeds Leeds LS2 9JT UK Tel: +44 (0)113 3435716 Fax: +44 (0)113 3435749 ________________________________________ From: bic-announce-bounces(a)bic.mni.mcgill.ca [bic-announce-bounces(a)bic.mni.mcgill.ca] On Behalf Of G. Bruce Pike, Prof. [bruce.pike(a)mcgill.ca] Sent: 20 November 2009 21:26 To: BIC Announce Announce Subject: [BIC-announce] Fwd: Post Doctoral Fellowship Position - Brain Imaging - Robarts FYI

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[Fwd: BNS job alert]
by awe1＠psych.york.ac.uk 20 Nov '09

20 Nov '09

---------------------------- Original Message ---------------------------- Subject: BNS job alert From: "Dana Samson" <dana.samson(a)nottingham.ac.uk> Date: Fri, November 20, 2009 2:10 pm To: undisclosed-recipients:; -------------------------------------------------------------------------- UCL is currently advertising a *Research Associate post*. The post is for a neuropsychologist or cognitive neuroscientist interested in investigating the neural mechanisms of executive processes in the prefrontal cortex. Closing date: 7 December 2009, 5pm Further details can be found on the BNS website: http://www.the-bns.org/other_jobs.html Dana Samson BNS Membership Secretary -- ________________________________________ Dr Dana Samson School of Psychology University of Nottingham University Park Nottingham NG7 2RD UK http://www.danasamson.me.uk http://www.springlab.org Tel: ++44 (0) 115 846 7433 Fax: ++44 (0) 115 951 5324 This message has been checked for viruses but the contents of an attachment may still contain software viruses which could damage your computer system: you are advised to perform your own checks. Email communications with the University of Nottingham may be monitored as permitted by UK legislation.

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TMS
by Antony Morland 18 Nov '09

18 Nov '09

Dear All, The TMS equipment has now moved into the Stimulus Preparation Room, off the open plan area. The door will be locked, but a key may be borrowed from reception to gain access. Please lock the door and return the key when you are finished. Best wishes Tony

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YNiC seminar postponed
by rem 17 Nov '09

17 Nov '09

Dear Users The ECR forum have organised a "Families in Science" event from 2-5 pm this Thursday that will be held in the Department of Psychology. Therefore there will not be a YNiC seminar this week. Best wishes Rebecca

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FW: University of York: Cell and Molecular Biology Lunch Club - Mon 16th November
by Antony Morland 12 Nov '09

12 Nov '09

Apologies for cross postings.. _____ From: Lisa Schubert [mailto:lisa.schubert@hyms.ac.uk] Sent: 12 November 2009 10:13 To: Lisa Schubert Subject: University of York: Cell and Molecular Biology Lunch Club - Mon 16th November If you would like to meet with Professor Miesenboeck during his visit, please contact Sean Sweeney (sts1(a)york.ac.uk) CELL AND MOLECULAR BIOLOGY LUNCH CLUB Monday 16th November 2009, 1.15pm Room K018, Biology Professor Geor Miesenboeck Department of Physiology, Anatomy and Genetics, Oxford "The beginnings of optogenetics " Abstract: Light-sensitive proteins encoded in DNA can serve as selective optical interfaces for observing and controlling genetically targeted neurons in functioning circuits, in vitro and in vivo. Light-emitting sensors of neuronal activity (reporting calcium increase, neurotransmitter release, or membrane depolarization) have begun to reveal how information is represented by neuronal assemblies, and how these representations are transformed during the computations that inform behaviour. Light-driven actuators control the electrical activity of central neurons in freely moving animals and establish causal connections between the activities of specific neurons and the expression of particular behaviours. The combination of finely resolved optical field sensing and finely resolved optical field actuation is opening new dimensions for the analysis of the connectivity, dynamics, and plasticity of neuronal circuits, and perhaps even for replacing lost---or designing novel---functionalities. Host: Sean Sweeney (sts1(a)york.ac.uk) -- Centre for Immunology and Infection Department of Biology and Hull York Medical School University of York P O Box 373 York YO10 5YW Tel: 01904 328845 Fax: 01904 328844 www.york.ac.uk/res/cii

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YNiC seminar TODAY
by rem 12 Nov '09

12 Nov '09

Dear Users 4-5 pm in YNiC open plan. Silvia Gennari will give a talk on "Effects of implied physical effort in sensory-motor and pre-frontal cortex during language comprehension". This talk will be based on the article by Claire Moody and Silvia Gennari that is currently "in press" in NeuroImage. Everyone is welcome to attend. Best wishes Rebecca Article title: Effects of implied physical effort in sensory-motor and pre-frontal cortex during language comprehension Reference: YNIMG6471 Journal title: Neuroimage Corresponding author: Dr. Silvia P. Gennari First author: Dr. Claire L. Moody Received at Elsevier: 27-JUL-2009 Final version published online: 17-OCT-2009 Full bibliographic details: Neuroimage 49 (2010), pp. 782-793 DOI information: 10.1016/j.neuroimage.2009.07.065

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Comparing MEG and fMRI
by awe1＠psych.york.ac.uk 09 Nov '09

09 Nov '09

The attached paper from the Helsinki group reporting direct comparisons of MEG and fMRI responses during the naming of objects and actions may be of interest. Andy

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YNiC seminar 12th November
by rem 09 Nov '09

09 Nov '09

Dear Users This week Silvia Gennari will give a talk on "Effects of implied physical effort in sensory-motor and pre-frontal cortex during language comprehension". This talk will be based on the article by Claire Moody and Silvia Gennari that is currently "in press" in NeuroImage. YNiC seminars take place from 4-5 pm in YNiC open plan. Everyone is welcome to attend. Best wishes Rebecca Article title: Effects of implied physical effort in sensory-motor and pre-frontal cortex during language comprehension Reference: YNIMG6471 Journal title: Neuroimage Corresponding author: Dr. Silvia P. Gennari First author: Dr. Claire L. Moody Received at Elsevier: 27-JUL-2009 Final version published online: 17-OCT-2009 Full bibliographic details: Neuroimage 49 (2010), pp. 782-793 DOI information: 10.1016/j.neuroimage.2009.07.065

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Open Plan reminder
by Sam Johnson 05 Nov '09

05 Nov '09

Hello all, Just a quick reminder that open plan will again be very busy between 13:00 and 15:30 this afternoon for the MSc course. Last week all the machines were in use so it's unlikely there'll be any space today. Thanks, Sam

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ynic seminar TODAY
by Rebecca E Millman 05 Nov '09

05 Nov '09

"Highlights from the Society for Neuroscience meeting" 4-5 pm in YNiC Open Plan Tony Morland and Tim Andrews will tell us about their trip to the SfN meeting in Chicago. Everyone is welcome to attend. -- Dr. Rebecca E. Millman York Neuroimaging Centre The Biocentre York Science Park York YO10 5DG Email: rem(a)ynic.york.ac.uk Tel: 01904 435 5373

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YNiC seminar tomorrow
by Gary Green 04 Nov '09

04 Nov '09

4-5 pm in YNiC Open Plan, this Thursday (5th) Tony Morland and Tim Andrews will tell us about their trip to the SfN in Chicago. "Highlights from the SfN meeting" All welcome Refreshments will be served as usual -- Gary Green York Neuroimaging Centre The Biocentre York Science Park Innovation Way Heslington York YO10 5DG http://www.ynic.york.ac.uk https://www.ynic.york.ac.uk/about-us/people/ggrg tel. +44 (0) 1904 435349 Secretary (Claire Fox) +44 (0) 1904 435329 fax +44 (0) 1904 435356 mobile +44 (0) 788 191 3004

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Talk at Psychology, Monday Nov 9, 4:30
by Silke Goebel 04 Nov '09

04 Nov '09

Learning and limits on adult plasticity for speech Dr Jason Zevin Sackler Institute for Psychobiology Weill Medical College of Cornell University New York, USA 4.30pm, Monday November 9 2009 Psychology A202 (Venables) One way to understand changes in plasticity over the course of development (e.g. sensitive period phenomena) is as a result of the process of learning itself. This is readily observed even in simple neural network models. Learning to categorize speech sounds in one's native language can be characterized as a process of tuning the perceptual system to the dimensions along which change is meaningful in that language. One consequence of this process is a diminished sensitivity to foreign language (L2) contrasts that differ along dimensions not contrastive in one's native phonetic inventory, which ultimately can result in failures to learn even after many years of exposure. This specialization is also reflected in the responses of a network of left-lateralized temporal and frontal cortical regions which respond differentially to native speech contrasts relative to unfamiliar L2 sounds and control stimuli not perceived as crossing a categorical boundary. I will present a series of studies combining behavioral, electroencephalographic and fMRI techniques to examine the traces of early experience on the adult speech perception system. ORGANISED BY JELENA MIRKOVIC -- Dr Silke Goebel Department of Psychology University of York Heslington York YO10 5DD UK Tel: +44 (0) 1904 43 2872 Email: s.goebel(a)psych.york.ac.uk Web: http://www.york.ac.uk/res/crl/sgoebel.html TMS Lab: http://www.york.ac.uk/res/tms

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Thursday seminar
by Garreth Prendergast 28 Oct '09

28 Oct '09

Greetings all, Tomorrow evening there will be a presentation by me on some of the clinical work we've been performing at the centre, an overview of upcoming clinical research projects and also a brief look at some MEG group analysis which i've recently done. It's in the early stages, but quite interesting. Hope to see you there, i'm sure we can find the stash of refreshments too. Thanks, Garreth

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Open Plan Busyness
by Sam Johnson 28 Oct '09

28 Oct '09

Hello all, Just a quick note to let people know that this Thursday afternoon (and in fact the next 6 or 7 Thursday afternoons) will be very busy in open plan with the MSc practical sessions. Due to the numbers it's unlikely you'll be able to get on the machines from about 13:00 till 15:30, as we expect almost, if not all the computers to be in use. More info to follow on the Thursday evening seminar. Thanks, Sam -- Sam Johnson Science Manager, York NeuroImaging Centre University of York http://www.ynic.york.ac.uk

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Useful stuff
by Philip Quinlan 28 Oct '09

28 Oct '09

Thank Chris Frith not me. Philip. ******************************************************************** Philip Quinlan E-Mail: ptq1(a)york.ac.uk Department of Psychology FAX: (01904) 433181 The University of York Tel: (01904) 430000 Ext. 3135 Heslington Direct : (01904) 433135 York YO10 5DD U.K. ******************************************************************** > >

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Important updates at YNiC
by Antony Morland 23 Oct '09

23 Oct '09

Dear All, As many of you may know, YNiC has introduced a new charging policy as of October this year. The new charging policy can be found at https://www.ynic.york.ac.uk/information/application. YNiC will now be charging investigators for the use of the facilities at YNiC in line with the policy. We have also updated the Project Proposal Form so it includes details of provisional financial arrangements for planned investigations at YNiC. It can also be found at https://www.ynic.york.ac.uk/information/application. Please note that many of you will be eligible for low charging rates because of your past efforts to raise funds for scanning or because you are a research student. Best wishes Tony

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Seminar Today at YNiC
by Gary Green 22 Oct '09

22 Oct '09

Today, (4-5 pm) in YNiC open plan, *22nd October: YNiC project proposal presentation* "The Nucleus Accumbens: A walk on the aversive side" Liat Levita, Department of Psychology. All welcome Refreshments will be available after the talk -- Gary Green York Neuroimaging Centre The Biocentre York Science Park Innovation Way Heslington York YO10 5DG http://www.ynic.york.ac.uk tel. 01904 435349 fax 01904 435356 mobile 0788 191 3004

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[Fwd: [SPM] PhD position available at UZ Brussels Belgium]
by Gary Green 19 Oct '09

19 Oct '09

FYI ------------------------------- PHD POSITION AT THE MEDICAL IMAGING DEPARTMENT, UZ BRUSSEL, VRIJE UNIVERSITEIT BRUSSEL The medical imaging department of the UZ Brussels is looking for a highly motivated PhD student to take part in an interdisciplinary research project entitled “ a semi- longitudinal neuroscientific study of bilingualism in development” in collaboration with the department of neuroradiology and linguistics. The research involves pediatric functional and structural MRI as well as DTI. The imaging department is equipped with a 3T Philips scanner. The MR facilities include stimulus equipment for fMRI, a TMS system, … The applicant must have a master degree (or equivalent) in physics, engineering, computer science, computational neuroscience or related field. Prior experience with Matlab and fMRI/EEG/PET data analysis as well as a background in neuroscience are preferred but not mandatory. Preference will be given to the candidate who is highly motivated to engage in a multidisciplinary team and innovative research. The project starts January 1st 2010 for a duration of 2 + 2 years. 2 Full time PhD positions are available. Applications, including a CV and a motivation letter, should be sent by email to kamondt(a)vub.ac.be before November 1st, 2009. For any complementary information, please contact Robert Luypaert (robert.luypaert(a)uzbrussel.be) or Katrien Mondt (kamondt(a)vub.ac.be) ------------------------------------------------------------------------ *Prof. dr. Katrien Mondt Vrije Universiteit Brussel * Faculteit Letteren & Wijsbegeerte Departement Taal- & Letterkunde Centrum voor Linguïstiek Pleinlaan 2 - 1050 Brussel Tel 00 32 2 629 2668 Gsm 00 32 486 560 525 Fax 00 32 2 629 3684 kamondt(a)vub.ac.be _ _ ------------------------------------------------------------------------

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YNiC seminar TODAY
by rem 15 Oct '09

15 Oct '09

Today 4-5 pm in YNiC open plan. Jing Kan from the Department of Computer Science will talk about "Basis functions source model applied to MEG Spatio-Temporal Source Reconstruction". Everyone is welcome to attend. Best wishes Rebecca Abstract: The aim of this paper is to explore a new method of MEG source spatio-temporal reconstruction based on modeling the neural source with extended spherical basis functions. The high resolution 3D cortical mesh is extracted along with the corresponding MRI scan. Inspired by the theory that Laplacian eigenvectors of spherical mesh are equivalent to its basis functions which represent the whole mesh, we build a new model that describes the source distributed on each mesh vertex. This model consists of analogous basis functions and unknown weighted coefficients. Along with the leadfield, the weighted coefficients can be calculated in the light of forward formula of MEG.. The distributed neural source on the mesh is then reconstructed according to the above Basis functions expanded model. Expanding this process from single time point to continuous time series, it is possible to obtain the spatio-temporal reconstructed neural source distributed on cortical mesh vertices. Finally, the method is implemented using real data for signal reconstruction experiments. The robustness of this MEG reconstruction solution is discussed by two aspects. One is to compare with classical methods, i.e. minimum-norm method. The other is to apply the algorithm into meshes with different resolutions. It is clear that these approaches provide a new angle and inspiration of computer graphics to MEG signal reconstruction. Key word: MEG,, inverse problem, eigen-decomposition, basis function, Laplacian eigenvector, spheroidal model, weighted coefficient, spatio-temporal source reconstruction

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[Fwd: [SPM] Job advertisement: Neuroimaging Lectureship at Bangor]
by Gary Green 14 Oct '09

14 Oct '09

I have been asked to forward the email below ----------------------------------- Dear Colleague There is a Lectureship open in the School of Psychology at Bangor, with a focus on neuroimaging. Details below. Paul BANGOR UNIVERSITY COLLEGE OF HEALTH & BEHAVIOURAL SCIENCES SCHOOL OF PSYCHOLOGY Lectureship (Assistant Professor equivalent) Grade 7: £29,704 - £35,469 p.a. We invite applications for a Lectureship (Assistant Professor equivalent) in the School of Psychology at Bangor University. The position carries a permanent contract, subject to a 3 year probationary review. With this appointment, we specifically aim to strengthen the School's research programme in MRI neuroimaging. We encourage applications from researchers working with neuroimaging methods in any area of inquiry. The School has an outstanding record of teaching (ranked "Excellent" for Teaching Quality) and research (7th of 76 UK Schools in the 2008 "Research Power" table, a combined metric of research quality and quantity). Our academics benefit from an excellent research environment, which includes: low teaching loads; numerous journal clubs and technical groups; School-funded PhD studentships prioritised for new staff; ample space for laboratories; MRI-guided TMS; several EEG labs; close links with the local NHS Trust that support specialist neurological and psychiatric patient panels; an ESRC-funded Bilingualism Centre; and the £5M Bangor-led Wales Institute of Cognitive Neuroscience that links researchers in Cardiff and Swansea. The School also benefits from its place in the College of Health and Behavioural Sciences, which includes excellent international research in areas such as motivation, exercise physiology, perceptual/motor performance, and clinical trials methodology. Our neuroimaging capacity is centred on a research-dedicated 3T Philips MRI scanner, housed within the School of Psychology. This facility is supported by a School-funded MR physicist and image analyst. Our neuroimaging research group, comprising >20 staff, postdocs, and PhD students, meets weekly to review recent literature and to discuss proposed projects and results. The group includes specialists in: patient studies and lesion reconstruction; high-level vision; working memory; attention; ageing; eye movements; neuropsychiatry; and spectroscopy. The School operates a generous access policy for the scanner, aimed at facilitating new projects for the benefit of publications and grant applications. Bangor is located in scenic North Wales, featuring stunning mountain and coastal landscapes, a clean and peaceful environment, and ready access to Birmingham, Manchester, Liverpool, and London. Application forms and further particulars should be obtained by contacting Human Resources, Bangor University; tel: (01248) 382926/388132; e-mail: personnel(a)bangor.ac.uk; web: www.bangor.ac.uk Please quote reference number 09-9/36 when applying. Closing date for applications: Tuesday 1st December, 2009. For further details and an informal discussion about the post, potential applicants are encouraged to contact Dr. Paul Downing, Deputy Head of School (Research), e-mail: p.downing(a)bangor.ac.uk. More information about the School can be found at http:// www.bangor.ac.uk/psychology/ More information about neuroimaging in the School is at http:// biu.psychology.bangor.ac.uk/ Committed To Equal Opportunities -- Gall y neges e-bost hon, ac unrhyw atodiadau a anfonwyd gyda hi, gynnwys deunydd cyfrinachol ac wedi eu bwriadu i'w defnyddio'n unig gan y sawl y cawsant eu cyfeirio ato (atynt). Os ydych wedi derbyn y neges e-bost hon trwy gamgymeriad, rhowch wybod i'r anfonwr ar unwaith a dilëwch y neges. Os na fwriadwyd anfon y neges atoch chi, rhaid i chi beidio â defnyddio, cadw neu ddatgelu unrhyw wybodaeth a gynhwysir ynddi. Mae unrhyw farn neu safbwynt yn eiddo i'r sawl a'i hanfonodd yn unig ac nid yw o anghenraid yn cynrychioli barn Prifysgol Bangor. Nid yw Prifysgol Bangor yn gwarantu bod y neges e-bost hon neu unrhyw atodiadau yn rhydd rhag firysau neu 100% yn ddiogel. Oni bai fod hyn wedi ei ddatgan yn uniongyrchol yn nhestun yr e-bost, nid bwriad y neges e-bost hon yw ffurfio contract rhwymol - mae rhestr o lofnodwyr awdurdodedig ar gael o Swyddfa Cyllid Prifysgol Bangor. www.bangor.ac.uk This email and any attachments may contain confidential material and is solely for the use of the intended recipient(s). If you have received this email in error, please notify the sender immediately and delete this email. If you are not the intended recipient(s), you must not use, retain or disclose any information contained in this email. Any views or opinions are solely those of the sender and do not necessarily represent those of the Bangor University. Bangor University does not guarantee that this email or any attachments are free from viruses or 100% secure. Unless expressly stated in the body of the text of the email, this email is not intended to form a binding contract - a list of authorised signatories is available from the Bangor University Finance Office. www.bangor.ac.uk

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[Fwd: Re: [SPM] Postdoctoral Position]
by Gary Green 13 Oct '09

13 Oct '09

FYI ----------------------- Dear Colleague, I am delighted to forward this potential opening (below) on behalf of Stefan With very best wishes, Karl Friston ------------------------- *Postdoctoral Researcher in High Speed MR Spectroscopic Imaging in Breast and Brain University of New Mexico, Albuquerque, NM, USA *The Department of Neurology at the University of New Mexico ( http://hsc.unm.edu/som/neuro/lab/) has an opening for a postdoctoral researcher to develop parallel echo-planar MR spectroscopic imaging methods using large scale RF array coils. NIH funded research to develop metabolite mapping in breast cancer for disease staging and treatment monitoring is conducted in collaboration with the Cancer Center (_http://cancer.unm.edu/_) and the breast MRI/MRS program at the University of Minnesota's Center for Magnetic Resonance Research (http://www.cmrr.umn.edu <http://www.cmrr.umn.edu/>). Development of metabolite mapping in brain for applications in Psychiatry and Neurology is carried out in a multi-center collaboration ( http://hsc.unm.edu/som/neuro/lab/pepsi.shtml). We are seeking candidates who are interested in parallel imaging, pulse sequence development, and spectroscopic data analysis. The candidate will work in an interdisciplinary team of clinicians and basic scientists and have access to state-of-the-art MRI and computational facilities. The successful candidate should be creative, able to work as part of a multi-disciplinary group with physicians, physicists, engineers and computer scientists, and should have good English communication skills. Experience with both high field MR spectroscopy and high-speed parallel MRI techniques, and a strong interest in medicine/biology will be preferred. Preferred qualifications for this position include: * PhD in MR physics, biophysics, biomedical engineering or related field * Experience developing pulse sequences and image reconstruction on the Siemens Syngo platform * Programming experience with Matlab or IDL, and C++ * A record of publication and conference proceedings Qualified candidates should submit their CV and three references to: Stefan Posse, PhD (sposse(a)unm.edu <mailto:sposse@unm.edu>), Department of Neurology, University of New Mexico School of Medicine, MSC 10 5620, 1 University of New Mexico, Albuquerque, NM 87131 Albuquerque offers excellent quality of life, beautiful scenery with mountains nearby and plenty of opportunities for outdoor sports, such as hiking and skiing. The University of New Mexico is an Equal Opportunity/Affirmative Action Employer and Educator. Qualified women and minorities are strongly encouraged to apply. -- Gary Green York Neuroimaging Centre The Biocentre York Science Park Innovation Way Heslington York YO10 5DG http://www.ynic.york.ac.uk https://www.ynic.york.ac.uk/about-us/people/ggrg tel. +44 (0) 1904 435349 Secretary (Claire Fox) +44 (0) 1904 435329 fax +44 (0) 1904 435356 mobile +44 (0) 788 191 3004

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[Fwd: Programmer position]
by Gary Green 13 Oct '09

13 Oct '09

FYI ----------------- Hi everyone - We are searching for a senior programmer to develop and implement tools for MRI data processing and analysis at the UT Imaging Research Center in Austin. If you know of anyone who might be interested, please pass this ad along to them. The official job posting is at: http://utdirect.utexas.edu/pnjobs/pnjobsvw.WBX?comp=0&job_nbr=091012019368 <http://utdirect.utexas.edu/pnjobs/pnjobsvw.WBX?comp=0&job_nbr=091012019368> Thanks, Russ -- Russell A. Poldrack Director, Imaging Research Center Professor of Psychology and Neurobiology University of Texas at Austin 3925-B W. Braker Ln. Austin, Texas 78759 Phone: 512.232.9504 Fax:512.232.4202 Email: poldrack(a)mail.utexas.edu <mailto:poldrack@mail.utexas.edu> Web: http://www.poldracklab.org

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YNiC seminar 15th October
by rem 12 Oct '09

12 Oct '09

Dear Users This Thursday (4-5 pm) in YNiC open plan, there will be a presentation by Jing Kan from the Department of Computer Science. The title of Jing's talk is "Basis functions source model applied to MEG Spatio-Temporal Source Reconstruction". Everyone is welcome to attend. Best wishes Rebecca Abstract: The aim of this paper is to explore a new method of MEG source spatio-temporal reconstruction based on modeling the neural source with extended spherical basis functions. The high resolution 3D cortical mesh is extracted along with the corresponding MRI scan. Inspired by the theory that Laplacian eigenvectors of spherical mesh are equivalent to its basis functions which represent the whole mesh, we build a new model that describes the source distributed on each mesh vertex. This model consists of analogous basis functions and unknown weighted coefficients. Along with the leadfield, the weighted coefficients can be calculated in the light of forward formula of MEG.. The distributed neural source on the mesh is then reconstructed according to the above Basis functions expanded model. Expanding this process from single time point to continuous time series, it is possible to obtain the spatio-temporal reconstructed neural source distributed on cortical mesh vertices. Finally, the method is implemented using real data for signal reconstruction experiments. The robustness of this MEG reconstruction solution is discussed by two aspects. One is to compare with classical methods, i.e. minimum-norm method. The other is to apply the algorithm into meshes with different resolutions. It is clear that these approaches provide a new angle and inspiration of computer graphics to MEG signal reconstruction. Key word: MEG,, inverse problem, eigen-decomposition, basis function, Laplacian eigenvector, spheroidal model, weighted coefficient, spatio-temporal source reconstruction

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