PsychoPy: “PsychoPy is an open-source application to allow the
presentation of stimuli and collection of data for a wide range of
neuroscience, psychology and psychophysics experiments.
It’s a free, powerful alternative to Presentation™ or e-Prime™ . It’s
written in Python (a free alternative to Matlab™ )”.
http://www.psychopy.org/
********************************************************************
Philip Quinlan E-Mail: ptq1(a)york.ac.uk
Department of Psychology FAX: (01904) 433181
The University of York Tel: (01904) 430000 Ext. 3135
Heslington Direct : (01904) 433135
York
YO10 5DD
U.K.
********************************************************************
Dear All,
Apparently, we are in the running for THE University of the Year. The
folks who make the decision are visiting YNiC tomorrow. To make a good
impression on them, I'd value the presence of those who are or have been
engaged in neuroimaging research at YNiC. The tour of YNiC starts at
4pm and should finish at 4:30pm.
Apologies for cross postings.
Thanks
Tony
Dear Users
Today (4-5 pm YNiC open plan) Miriam Johnson from the Hull York
Medical School will give a talk on "Magnetoencephalography appearances
in breathless patients with and without air flow directed to the face."
Everyone is welcome to attend.
Best wishes
Rebecca
Background: Intractable breathlessness is a common and devastating
consequence of many diseases. Breathlessness affects all aspects of
life, causing major distress for both patient and caregiver. Many
patients face psychological, social and physical repercussions of
persistent breathlessness, which require, long-term NHS support
especially out of hours.
Research into possible mechanisms for the perception of breathlessness
has largely concentrated on peripheral pathways. However there is a
growing interest in functional brain imaging using positron electron
tomography scanning and functional MRI (fMRI), mainly in induced
breathlessness in healthy volunteers. Similarities with pain perception
are striking. However, little is known of these processes in patients
with chronic breathlessness due to lung disease, indeed, one study
suggests that patients with asthma demonstrate habituation and
down-regulation of perceived unpleasantness due to breathlessness.
Moreover we know nothing of the effect of interventions to improve
breathlessness; patients with chronic breathlessness tolerate fMRI
poorly. Magnetoencephalography (MEG) scanning is a possibly tolerated
method but has not been tried.
There is some clinical evidence that the use of a handheld fan reduces
the sensation of breathlessness and may reduce the need for nebulisers
and oxygen. The fan directs airflow to the area innervated by the 2nd
and 3rd branches of the trigeminal nerve. It is universally available,
cheap, non-invasive and easy to use in any setting alongside any other
breathlessness intervention with no contra-indications. As the cost to
the NHS of oxygen, nebulisers and inhalers and hospital admission are
considerable, this area warrants research both with regard to clinical
effect but also to mechanism of action.
--
Dr. Rebecca E. Millman
York Neuroimaging Centre
The Biocentre
York Science Park
York
YO10 5DG
Email: rem(a)ynic.york.ac.uk
Tel: 01904 435 5373
I ran 3 identical first level FSL analyses of a localiser scan in order to
compare the different bet settings (applied to all structural and functional
images). I can confirm that BET with the recursive flag (-R) produces the
best outcomes with higher Z values when transformed to standard space. The
-B option looks good when examining the resulting BET images, and deals
nicely with residual neck artefacts, but actually produces worse results at
the level of the statistics.
Below are images showing zstats from each first level analysis (face-place
localiser), converted to standard space and displayed on the MNI brain.
PPA (blue), FFA (orange), standard space - BET with no options
http://i.imgur.com/q3FdX.png
PPA (blue), FFA (orange), standard space - BET with -B option
http://i.imgur.com/QC9al.png
PPA (blue), FFA (orange), standard space - BET with recursive option (-R)
http://i.imgur.com/Nqob1.png
Activation is more extensive and more significant with the -R option.
Images of the structural scans after each bet extraction can be seen in the
album below
http://laserdragon.imgur.com/brainimaging
It seems that the standard pipeline involves using the -R option anyway, but
I thought people might be interested to see the difference it makes, and
that the -B option turns out to be pretty bad.
Chris
On Mon, 13, Sep, 2010 at 05:53:51PM +0100, Chris Racey spoke thus..
> Actually, after my last message, Padraig came to see me and mentioned
> another option -R which iteratively repeats the BET procedure from different
> starting points. He suggested that this may achieve the same improved
> result. I tried this option instead and indeed it does still seem to be an
> improvement. However it runs considerably quicker and doesn't seem to result
> in intensity changes in the image.
That was going to be my suggestion too. I don't now normally run bet
without using the -R flag. As Andre says, changing the starting co-ords
can also help - for the record, the standard automatic cleanup for the
structural scans currently uses -c 90 116 166 but doesn't use -R. I'm
not entirely sure why it doesn't as I thought it did (and was about to
say it did until I double checked).
I'll probably change this to use -R by default (for the automatic ones)
unless someone can remind me why it doesn't...
Mark
--
Mark Hymers
York Neuroimaging Centre
the -c option flag too can be useful and has virtually no cost .. this
simple sets the centre of gravity to which the initial sphere is fitted.
find the coordinates of the AC in your participant (slice numbers) set
the -c flag to this and usually the initial extraction is vastly improved.
Andre'
Chris Racey wrote:
> Thanks Tony,
>
> That's a good point, I will be in a position to do this comparison in the
> next day or so, after the analysis I'm running finishes.
>
> Actually, after my last message, Padraig came to see me and mentioned
> another option -R which iteratively repeats the BET procedure from different
> starting points. He suggested that this may achieve the same improved
> result. I tried this option instead and indeed it does still seem to be an
> improvement. However it runs considerably quicker and doesn't seem to result
> in intensity changes in the image.
>
> I will investigate the results of these procedures on statistical outcomes
> and post a comparison in the next couple of days.
>
> Chris
>
> -----Original Message-----
> From: ynic-users-bounces(a)ynic.york.ac.uk
> [mailto:ynic-users-bounces@ynic.york.ac.uk] On Behalf Of
> am501(a)psych.york.ac.uk
> Sent: 13 September 2010 17:43
> To: Chris Racey
> Cc: ynic-users(a)ynic.york.ac.uk
> Subject: Re: BET settings
>
> Thanks for this Chris. Have you any side by side fMRI analysis with and
> without the -B option? Ti would be interesting to see whether or the
> results of statistical treatments change and in what way.
>
> Tony
>
>> Hi all,
>>
>>
>>
>> I was having some problems bet extracting some of my structural scans, I
>> was
>> getting a lot of left over neck that was screwing up the alignment. I
>> noticed the current version of bet has a new option flag (to me at least),
>> which focuses on cleaning up the neck.
>>
>>
>>
>> The option is -B . When using this flag the processing takes considerably
>> longer, something along the lines of 10-15 mins per scan. However, not
>> only
>> did it resolve the issue, but the resulting image looks cleaner and more
>> precise than I would expect from a normal bet. I've attached a comparison
>> image so you can see the effect.
>>
>>
>>
>> I did similar comparisons running this flag with functional data and it
>> also
>> shows improvements. At the moment I'm re-processing my data files in this
>> way before running my analysis.
>>
>>
>>
>> I thought I'd mention this in case it might be a useful option for other
>> people to use, but also in case anyone knows any reason why it might be
>> problematic. I'd be keen to know if anyone knows of any reason why I
>> shouldn't use it? I notice the overall intensity seems slightly lower when
>> this flag has been used, is this likely to be a problem?
>>
>>
>>
>> Cheers,
>>
>> Chris Racey
>>
>> --
>> ynic-users mailing list
>> ynic-users(a)ynic.york.ac.uk
>> https://www.ynic.york.ac.uk/mailman/listinfo/ynic-users
>>
>
>
>
> --
> ynic-users mailing list
> ynic-users(a)ynic.york.ac.uk
> https://www.ynic.york.ac.uk/mailman/listinfo/ynic-users
>
>
> --
> ynic-users mailing list
> ynic-users(a)ynic.york.ac.uk
> https://www.ynic.york.ac.uk/mailman/listinfo/ynic-users
--
Andre'
************************************************************************
Andre Gouws
York Neuroimaging Centre
The Biocentre
York Science Park
Heslington
YO10 5DG
Tel: +44 (0) 1904 435327
Fax: +44 (0) 1904 435356
Thanks for this Chris. Have you any side by side fMRI analysis with and
without the -B option? Ti would be interesting to see whether or the
results of statistical treatments change and in what way.
Tony
> Hi all,
>
>
>
> I was having some problems bet extracting some of my structural scans, I
> was
> getting a lot of left over neck that was screwing up the alignment. I
> noticed the current version of bet has a new option flag (to me at least),
> which focuses on cleaning up the neck.
>
>
>
> The option is -B . When using this flag the processing takes considerably
> longer, something along the lines of 10-15 mins per scan. However, not
> only
> did it resolve the issue, but the resulting image looks cleaner and more
> precise than I would expect from a normal bet. I've attached a comparison
> image so you can see the effect.
>
>
>
> I did similar comparisons running this flag with functional data and it
> also
> shows improvements. At the moment I'm re-processing my data files in this
> way before running my analysis.
>
>
>
> I thought I'd mention this in case it might be a useful option for other
> people to use, but also in case anyone knows any reason why it might be
> problematic. I'd be keen to know if anyone knows of any reason why I
> shouldn't use it? I notice the overall intensity seems slightly lower when
> this flag has been used, is this likely to be a problem?
>
>
>
> Cheers,
>
> Chris Racey
>
> --
> ynic-users mailing list
> ynic-users(a)ynic.york.ac.uk
> https://www.ynic.york.ac.uk/mailman/listinfo/ynic-users
>
Hi all,
I was having some problems bet extracting some of my structural scans, I was
getting a lot of left over neck that was screwing up the alignment. I
noticed the current version of bet has a new option flag (to me at least),
which focuses on cleaning up the neck.
The option is -B . When using this flag the processing takes considerably
longer, something along the lines of 10-15 mins per scan. However, not only
did it resolve the issue, but the resulting image looks cleaner and more
precise than I would expect from a normal bet. I've attached a comparison
image so you can see the effect.
I did similar comparisons running this flag with functional data and it also
shows improvements. At the moment I'm re-processing my data files in this
way before running my analysis.
I thought I'd mention this in case it might be a useful option for other
people to use, but also in case anyone knows any reason why it might be
problematic. I'd be keen to know if anyone knows of any reason why I
shouldn't use it? I notice the overall intensity seems slightly lower when
this flag has been used, is this likely to be a problem?
Cheers,
Chris Racey
Dear Users
This week (4-5 pm YNiC open plan) Miriam Johnson from the Hull York
Medical School will give a talk on "Magnetoencephalography appearances
in breathless patients with and without air flow directed to the face."
Everyone is welcome to attend.
Best wishes
Rebecca
Background: Intractable breathlessness is a common and devastating
consequence of many diseases. Breathlessness affects all aspects of
life, causing major distress for both patient and caregiver. Many
patients face psychological, social and physical repercussions of
persistent breathlessness, which require, long-term NHS support
especially out of hours.
Research into possible mechanisms for the perception of breathlessness
has largely concentrated on peripheral pathways. However there is a
growing interest in functional brain imaging using positron electron
tomography scanning and functional MRI (fMRI), mainly in induced
breathlessness in healthy volunteers. Similarities with pain perception
are striking. However, little is known of these processes in patients
with chronic breathlessness due to lung disease, indeed, one study
suggests that patients with asthma demonstrate habituation and
down-regulation of perceived unpleasantness due to breathlessness.
Moreover we know nothing of the effect of interventions to improve
breathlessness; patients with chronic breathlessness tolerate fMRI
poorly. Magnetoencephalography (MEG) scanning is a possibly tolerated
method but has not been tried.
There is some clinical evidence that the use of a handheld fan reduces
the sensation of breathlessness and may reduce the need for nebulisers
and oxygen. The fan directs airflow to the area innervated by the 2nd
and 3rd branches of the trigeminal nerve. It is universally available,
cheap, non-invasive and easy to use in any setting alongside any other
breathlessness intervention with no contra-indications. As the cost to
the NHS of oxygen, nebulisers and inhalers and hospital admission are
considerable, this area warrants research both with regard to clinical
effect but also to mechanism of action.
--
************************************************************************
Dr. Rebecca E. Millman
Science Liaison Officer
York Neuroimaging Centre
The Biocentre
York Science Park
Heslington
YO10 5DG
Tel: +44 (0) 1904 567614
Fax: +44 (0) 1904 435356
FYI
****************************************************************
Dr. Ekaterini Klepousniotou
Lecturer in Cognitive Neuroscience & Neuropsychology
Institute of Psychological Sciences
University of Leeds
Leeds LS2 9JT
UK
Tel: +44 (0)113 3435716
Fax: +44 (0)113 3435749
From: nlc_distribution-bounces(a)nlc2009.angularis.org [mailto:nlc_distribution-bounces@nlc2009.angularis.org] On Behalf Of Kate Watkins
Sent: 07 September 2010 10:01
To: nlc_distribution(a)nlc2009.angularis.org
Subject: [NLC2009] Postdoctoral and graduate RA positions University of Oxford
We are advertising two jobs (one graduate research assistant and one postdoctoral researcher) in the Speech and Brain Research Group ((http://www.fmrib.ox.ac.uk/speech-and-brain) at the University of Oxford - Department of Experimental Psychology and FMRIB Centre.
The research will investigate interactions between auditory and motor areas in the brain during speech perception and production. The project will employ a variety of techniques either separately or in combination; these include behavioural measures, TMS, MEG and functional MRI.
Both positions are funded from 1 January 2011 for two years in the first instance with the possibility of renewal.
Initial scientific enquiries about the post or the project may be directed to Dr Kate Watkins (email: kate.watkins(a)psy.ox.ac.uk<mailto:kate.watkins@psy.ox.ac.uk>) or Dr Riikka Mottonen (email: riikka.mottonen(a)psy.ox.ac.uk<mailto:riikka.mottonen@psy.ox.ac.uk>).
Further particulars, including instructions on applying for these posts and a copy of the application form, are available from the Administration Offices (email: applications(a)psy.ox.ac.uk) or can be accessed on the departmental website at http://www.psy.ox.ac.uk/. The closing date for applications is 12 noon on 8 October 2010. Please quote reference number CQ/10/013 (postdoc) CQ/10/014 (graduate) on all correspondence. Interviews are scheduled for the end of October 2010.
Kate Watkins, PhD
University Lecturer in
Department of Experimental Psychology
South Parks Road, Oxford, OX1 3UD
Tel: +44 (0)1865 271314 / 222581
http://www.fmrib.ox.ac.uk/speech-and-brain
Dear Colleagues
Today, Professor Shoogo Ueno from Japan will be giving the IEEE
Magnetics Society Distinguished Lecturers seminar in York. The title is
"Biomagnetics: An Interdisciplinary Field Where Magnetics, Biology, and
Medicine Overlap"
Professor Ueno writes..
This lecture focuses on the advances in biomagnetics and bioimaging
obtained mostly in our laboratory in recent years. The
lecture describes: (1) a method of localized magnetic stimulation of the
human brain by TMS with a figure-eight coil; (2) magneto-
encephalography (MEG) to measure extremely weak magnetic fields produced
from brain electrical activity using superconducting
quantum interference device (SQUID) systems; (3) impedance MRI and
current MRI; (4) cancer therapy and control of iron-ion
release from, and uptake into, ferritin, an iron-storage protein, by
using both high frequency and pulsed magnetic fields and
magnetic nanoparticles; and (5) magnetic control of biological cell
orientation and cell growth by strong static magnetic fields.
These new biomagnetic approaches will open new horizons in brain
research, brain treatment, and regenerative medicine.
The seminar will be in PX001 in the Exhibition Centre of the University,
at 14:00 on the 2nd of September.
All welcome
--
Gary Green
York Neuroimaging Centre
The Biocentre
York Science Park
Innovation Way
Heslington
York
YO10 5DG
http://www.ynic.york.ac.ukhttps://www.ynic.york.ac.uk/about-us/people/ggrg
tel. +44 (0) 1904 435349
PA (Richard Lee) +44 (0) 1904 435329
fax +44 (0) 1904 435356
mobile +44 (0) 788 191 3004
Dear Colleagues
Next week, Professor Shoogo Ueno from Japan will be giving the IEEE
Magnetics Society Distinguished Lecturers seminar in York. The title is
"Biomagnetics: An Interdisciplinary Field Where Magnetics, Biology, and
Medicine Overlap"
Professor Ueno writes..
This lecture focuses on the advances in biomagnetics and bioimaging
obtained mostly in our laboratory in recent years. The
lecture describes: (1) a method of localized magnetic stimulation of the
human brain by TMS with a figure-eight coil; (2) magneto-
encephalography (MEG) to measure extremely weak magnetic fields produced
from brain electrical activity using superconducting
quantum interference device (SQUID) systems; (3) impedance MRI and
current MRI; (4) cancer therapy and control of iron-ion
release from, and uptake into, ferritin, an iron-storage protein, by
using both high frequency and pulsed magnetic fields and
magnetic nanoparticles; and (5) magnetic control of biological cell
orientation and cell growth by strong static magnetic fields.
These new biomagnetic approaches will open new horizons in brain
research, brain treatment, and regenerative medicine.
details of the talk and a short biography of Professor Ueno are in the
attachment to this email
The seminar will be in PX001 in the Exhibition Centre of the University,
at 14:00 on the 2nd of September.
All welcome
--
Gary Green
York Neuroimaging Centre
The Biocentre
York Science Park
Innovation Way
Heslington
York
YO10 5DG
http://www.ynic.york.ac.ukhttps://www.ynic.york.ac.uk/about-us/people/ggrg
tel. +44 (0) 1904 435349
PA (Richard Lee) +44 (0) 1904 435329
fax +44 (0) 1904 435356
mobile +44 (0) 788 191 3004
We recently carried out an MRI study and (to keep it simple) we
compared two conditions A and B.
We found two regions that preferred A to B, region 1 and 2,
respectively.
I was keen to explore the time series a little further. So what I did
was take the A-B difference for each subject in each of the regions
and compute the 95%CI for each 2 sec interval from the start of the
stimulus presentation.
We get a difference time series for each region and for each point
we have a 95%CI. I have plotted the CIs for each point on each
function (one for region 1 and one for region 2).
Now I note at which time point the CIs reflect a sig diff (i.e., dont
cross the x axis) and what I find is that the critical difference
occurs earlier for region 1 than 2. At last a window on the time
course of psychological functioning?
I, of course, now want to claim my Nobel Prize but suspect this is
completely flawed.
Please advise.
Philip.
********************************************************************
Philip Quinlan E-Mail: ptq1(a)york.ac.uk
Department of Psychology FAX: (01904) 433181
The University of York Tel: (01904) 430000 Ext. 3135
Heslington Direct : (01904) 433135
York
YO10 5DD
U.K.
********************************************************************
I would be very grateful if the person who borrowed the book on
Magnetic Resonance Spectroscopy
edited by Matthews
could return it,
thanks
Gary
--
Gary Green
York Neuroimaging Centre
The Biocentre
York Science Park
Innovation Way
Heslington
York
YO10 5DG
http://www.ynic.york.ac.ukhttps://www.ynic.york.ac.uk/about-us/people/ggrg
tel. +44 (0) 1904 435349
PA (Richard Lee) +44 (0) 1904 435329
fax +44 (0) 1904 435356
mobile +44 (0) 788 191 3004
http://www.hindawi.com/journals/ijmms/2010/769780.html
********************************************************************
Philip Quinlan E-Mail: ptq1(a)york.ac.uk
Department of Psychology FAX: (01904) 433181
The University of York Tel: (01904) 430000 Ext. 3135
Heslington Direct : (01904) 433135
York
YO10 5DD
U.K.
********************************************************************
There is an additional seminar today
At 2pm
There will be a talk entitled
"NMR and MRI sensitivity enhancement by Parahydrogen Induced Polarization"
by
Kerstin Münnemann
Max Planck Institute for Polymer Research, Mainz, Germany
Despite its wide applicability in chemistry, biology and medicine,
Nuclear Magnetic Resonance (NMR) spectroscopy still suffers from its
inherently low sensitivity. Exploiting the large signal enhancements
associated with hyperpolarization techniques, such as Parahydrogen
Induced Polarization (PHIP), however, NMR or MRI qualify for monitoring
dynamic processes in real time. In this lecture, the synthesis and
hyperpolarization of several biocompatible molecules like barbiturates,
Vinylpyrrolinidon (blood plasma expander) or Dimethylcarboxylat
(precursor to fumarate) will be presented. Polarization transfer to 13C
in these molecules by using adequate pulse sequences is demonstrated.
Moreover, constant NMR signal enhancement of 1H and 13C is shown using a
continuous delivery of parahydrogen by hollow fiber membranes. This
allows the acquisition of two-dimensional NMR experiments requiring
multiple excitations with constant initial polarization. The membrane
technique can be easily extended to produce a continuous flow of a
hyperpolarized liquid as will be shown for MRI applications.
All welcome
Dear Users
Dear Users
Today (4-5 pm YNiC open plan) Matt Brookes from the University of
Nottingham will give a talk on "Brain network measurements using MEG
and ultra-high field MRI".
http://www.nottingham.ac.uk/neuroscience/contact/a-z/A-F/brookes_matt.phtml
Everyone is welcome to attend.
Best wishes
Rebecca
--
Dr. Rebecca E. Millman
York Neuroimaging Centre
The Biocentre
York Science Park
York
YO10 5DG
Email: rem(a)ynic.york.ac.uk
Tel: 01904 435 5373
FYI
-----------
*MRC Cognition and Brain Sciences Unit -- Cambridge*
*Neuroimaging Methods Post to Study Ageing*
The MRC Cognition and Brain Sciences Unit is an internationally renowned
research institute with state-of-the-art cognitive neuroscience
facilities, including Siemens 3T MRI and 306-channel Elekta-Neuromag MEG
scanners.
A 2 year post-doctoral position is available to support the
newly-established Cambridge Centre for Ageing and Neuroscience (CamCAN),
funded by the UK BBSRC in order to relate changes in the brain with
changes in cognitive function across the adult lifespan. You will be
part of a Cambridge-wide collaboration, working to develop and maintain
the storage and analysis pipelines for large quantities of MRI, fMRI and
MEG data. This post will be available from January 2011.
You will have a PhD in neuroscience, scientific computing or a related
area, plus experience of analysis of neuroimaging data, such as MRI,
fMRI and/or MEG. You should have excellent IT skills, being familiar
with Linux and Matlab, and ideally with specialised neuroimaging
analysis software. Experience of studying changes in the brain with
ageing, and of cognitive neuroscience would be an advantage. You will be
thorough, efficient, effective, a good communicator, and enjoy working
as part of a diverse and energetic team.
The starting salary will be in the range of £26,022 - £31,758 depending
upon qualifications and experience. We offer a flexible pay and reward
policy, 30 days annual leave entitlement, and an optional MRC final
salary Pension Scheme. On site car and cycle parking is available.
For informal discussion please contact Drs Rhodri Cusack or Rik Henson
by email: _rhodri.cusack(a)mrc-cbu.cam.ac.uk_
<mailto:rhodri.cusack@mrc-cbu.cam.ac.uk>/_rik.henson(a)mrc-cbu.cam.ac.uk_
<mailto:rik.henson@mrc-cbu.cam.ac.uk>.
Applications for this role must be made on line at
_http://jobs.mrc.ac.uk_ <http://jobs.mrc.ac.uk/>. If you do not have
internet access or experience technical difficulties, please contact
01793 867162, quoting reference* CBSU10/338*.
If you would like to receive this advert in large print, Braille, audio,
or electronic format/ hard copy, please contact the Recruitment team at
the MRC Shared Service Centre on the telephone number above or
_recruitment(a)ssc.mrc.ac.uk_ <mailto:recruitment@ssc.mrc.ac.uk>
*Closing Date: 20**^th ** August 2010*
The Medical Research Council is an Equal Opportunities Employer.
-------------------------------------------------------
Dr Richard Henson
Assistant Director, Neuroimaging
MRC Cognition & Brain Sciences Unit
15 Chaucer Road
Cambridge, CB2 7EF, UK
Office: +44 (0)1223 355 294 x522
Mob: +44 (0)794 1377 345
Fax: +44 (0)1223 359 062
http://www.mrc-cbu.cam.ac.uk/people/rik.henson/personal
-------------------------------------------------------
Hi,
As I mentioned a while back, just before the start of next term
(September 2010) we'll change the default Matlab version to R2010a
(7.10). This is just a reminder that it would be helpful if people
could quickly check that any extra toolboxes or scripts which they rely
on still work under 7.10 and let me know of any problems they see. If
we don't get any reports, we'll assume that it's all ok.
R2009a (7.8) will still be available until September 2011 as shown at:
https://www.ynic.york.ac.uk/doc/ITPages/FAQ/Misc/SupportedVersions#Matlab
Thank you,
Mark
--
Mark Hymers
York Neuroimaging Centre
Dear Users
This week (4-5 pm YNiC open plan) Matt Brookes from the University of
Nottingham will give a talk on "Brain network measurements using MEG and
ultra-high field MRI".
http://www.nottingham.ac.uk/neuroscience/contact/a-z/A-F/brookes_matt.phtml
Everyone is welcome to attend.
Best wishes
Rebecca
--
************************************************************************
Dr. Rebecca E. Millman Science Liaison Officer York Neuroimaging Centre
The Biocentre York Science Park Heslington YO10 5DG Tel: +44 (0) 1904
567614 Fax: +44 (0) 1904 435356
Apologies for cross-posting this to people in several email lists
Next week we have two seminars on Thursday the 29th in the YNiC Open
Plan area.
At 2pm
There will be a talk entitled
"NMR and MRI sensitivity enhancement by Parahydrogen Induced Polarization"
by
Kerstin Münnemann
Max Planck Institute for Polymer Research, Mainz, Germany
Despite its wide applicability in chemistry, biology and medicine,
Nuclear Magnetic Resonance (NMR) spectroscopy still suffers from its
inherently low sensitivity. Exploiting the large signal enhancements
associated with hyperpolarization techniques, such as Parahydrogen
Induced Polarization (PHIP), however, NMR or MRI qualify for monitoring
dynamic processes in real time. In this lecture, the synthesis and
hyperpolarization of several biocompatible molecules like barbiturates,
Vinylpyrrolinidon (blood plasma expander) or Dimethylcarboxylat
(precursor to fumarate) will be presented. Polarization transfer to 13C
in these molecules by using adequate pulse sequences is demonstrated.
Moreover, constant NMR signal enhancement of 1H and 13C is shown using a
continuous delivery of parahydrogen by hollow fiber membranes. This
allows the acquisition of two-dimensional NMR experiments requiring
multiple excitations with constant initial polarization. The membrane
technique can be easily extended to produce a continuous flow of a
hyperpolarized liquid as will be shown for MRI applications.
All are welcome
A separate email will announce the 4pm talk
Gary
--
Gary Green
York Neuroimaging Centre
The Biocentre
York Science Park
Innovation Way
Heslington
York
YO10 5DG
http://www.ynic.york.ac.ukhttps://www.ynic.york.ac.uk/about-us/people/ggrg
tel. +44 (0) 1904 435349
PA (Richard Lee) +44 (0) 1904 435329
fax +44 (0) 1904 435356
mobile +44 (0) 788 191 3004
Hello all,
Just to let people know there there are a couple of visits to YNiC this
week that might have an impact on you. Tomorrow (Tuesday) between 1:30
and about 2:30, and Wednesday morning, between 10 and 11 there will be
groups in open plan. Both groups are pretty small and won't be using the
computers so hopefully it won't be too disruptive. There will however be
presentations, so you may rather have a late lunch tomorrow and a
prolonged coffee on Wednesday.
Thanks, and apologies for any inconvenience,
Sam