Dear Users
This week (4-5 pm YNiC open plan) Miriam Johnson from the Hull York
Medical School will give a talk on "Magnetoencephalography appearances
in breathless patients with and without air flow directed to the face."
Everyone is welcome to attend.
Best wishes
Rebecca
Background: Intractable breathlessness is a common and devastating
consequence of many diseases. Breathlessness affects all aspects of
life, causing major distress for both patient and caregiver. Many
patients face psychological, social and physical repercussions of
persistent breathlessness, which require, long-term NHS support
especially out of hours.
Research into possible mechanisms for the perception of breathlessness
has largely concentrated on peripheral pathways. However there is a
growing interest in functional brain imaging using positron electron
tomography scanning and functional MRI (fMRI), mainly in induced
breathlessness in healthy volunteers. Similarities with pain perception
are striking. However, little is known of these processes in patients
with chronic breathlessness due to lung disease, indeed, one study
suggests that patients with asthma demonstrate habituation and
down-regulation of perceived unpleasantness due to breathlessness.
Moreover we know nothing of the effect of interventions to improve
breathlessness; patients with chronic breathlessness tolerate fMRI
poorly. Magnetoencephalography (MEG) scanning is a possibly tolerated
method but has not been tried.
There is some clinical evidence that the use of a handheld fan reduces
the sensation of breathlessness and may reduce the need for nebulisers
and oxygen. The fan directs airflow to the area innervated by the 2nd
and 3rd branches of the trigeminal nerve. It is universally available,
cheap, non-invasive and easy to use in any setting alongside any other
breathlessness intervention with no contra-indications. As the cost to
the NHS of oxygen, nebulisers and inhalers and hospital admission are
considerable, this area warrants research both with regard to clinical
effect but also to mechanism of action.
--
************************************************************************
Dr. Rebecca E. Millman
Science Liaison Officer
York Neuroimaging Centre
The Biocentre
York Science Park
Heslington
YO10 5DG
Tel: +44 (0) 1904 567614
Fax: +44 (0) 1904 435356
FYI
****************************************************************
Dr. Ekaterini Klepousniotou
Lecturer in Cognitive Neuroscience & Neuropsychology
Institute of Psychological Sciences
University of Leeds
Leeds LS2 9JT
UK
Tel: +44 (0)113 3435716
Fax: +44 (0)113 3435749
From: nlc_distribution-bounces(a)nlc2009.angularis.org [mailto:nlc_distribution-bounces@nlc2009.angularis.org] On Behalf Of Kate Watkins
Sent: 07 September 2010 10:01
To: nlc_distribution(a)nlc2009.angularis.org
Subject: [NLC2009] Postdoctoral and graduate RA positions University of Oxford
We are advertising two jobs (one graduate research assistant and one postdoctoral researcher) in the Speech and Brain Research Group ((http://www.fmrib.ox.ac.uk/speech-and-brain) at the University of Oxford - Department of Experimental Psychology and FMRIB Centre.
The research will investigate interactions between auditory and motor areas in the brain during speech perception and production. The project will employ a variety of techniques either separately or in combination; these include behavioural measures, TMS, MEG and functional MRI.
Both positions are funded from 1 January 2011 for two years in the first instance with the possibility of renewal.
Initial scientific enquiries about the post or the project may be directed to Dr Kate Watkins (email: kate.watkins(a)psy.ox.ac.uk<mailto:kate.watkins@psy.ox.ac.uk>) or Dr Riikka Mottonen (email: riikka.mottonen(a)psy.ox.ac.uk<mailto:riikka.mottonen@psy.ox.ac.uk>).
Further particulars, including instructions on applying for these posts and a copy of the application form, are available from the Administration Offices (email: applications(a)psy.ox.ac.uk) or can be accessed on the departmental website at http://www.psy.ox.ac.uk/. The closing date for applications is 12 noon on 8 October 2010. Please quote reference number CQ/10/013 (postdoc) CQ/10/014 (graduate) on all correspondence. Interviews are scheduled for the end of October 2010.
Kate Watkins, PhD
University Lecturer in
Department of Experimental Psychology
South Parks Road, Oxford, OX1 3UD
Tel: +44 (0)1865 271314 / 222581
http://www.fmrib.ox.ac.uk/speech-and-brain
Dear Colleagues
Today, Professor Shoogo Ueno from Japan will be giving the IEEE
Magnetics Society Distinguished Lecturers seminar in York. The title is
"Biomagnetics: An Interdisciplinary Field Where Magnetics, Biology, and
Medicine Overlap"
Professor Ueno writes..
This lecture focuses on the advances in biomagnetics and bioimaging
obtained mostly in our laboratory in recent years. The
lecture describes: (1) a method of localized magnetic stimulation of the
human brain by TMS with a figure-eight coil; (2) magneto-
encephalography (MEG) to measure extremely weak magnetic fields produced
from brain electrical activity using superconducting
quantum interference device (SQUID) systems; (3) impedance MRI and
current MRI; (4) cancer therapy and control of iron-ion
release from, and uptake into, ferritin, an iron-storage protein, by
using both high frequency and pulsed magnetic fields and
magnetic nanoparticles; and (5) magnetic control of biological cell
orientation and cell growth by strong static magnetic fields.
These new biomagnetic approaches will open new horizons in brain
research, brain treatment, and regenerative medicine.
The seminar will be in PX001 in the Exhibition Centre of the University,
at 14:00 on the 2nd of September.
All welcome
--
Gary Green
York Neuroimaging Centre
The Biocentre
York Science Park
Innovation Way
Heslington
York
YO10 5DG
http://www.ynic.york.ac.ukhttps://www.ynic.york.ac.uk/about-us/people/ggrg
tel. +44 (0) 1904 435349
PA (Richard Lee) +44 (0) 1904 435329
fax +44 (0) 1904 435356
mobile +44 (0) 788 191 3004
Dear Colleagues
Next week, Professor Shoogo Ueno from Japan will be giving the IEEE
Magnetics Society Distinguished Lecturers seminar in York. The title is
"Biomagnetics: An Interdisciplinary Field Where Magnetics, Biology, and
Medicine Overlap"
Professor Ueno writes..
This lecture focuses on the advances in biomagnetics and bioimaging
obtained mostly in our laboratory in recent years. The
lecture describes: (1) a method of localized magnetic stimulation of the
human brain by TMS with a figure-eight coil; (2) magneto-
encephalography (MEG) to measure extremely weak magnetic fields produced
from brain electrical activity using superconducting
quantum interference device (SQUID) systems; (3) impedance MRI and
current MRI; (4) cancer therapy and control of iron-ion
release from, and uptake into, ferritin, an iron-storage protein, by
using both high frequency and pulsed magnetic fields and
magnetic nanoparticles; and (5) magnetic control of biological cell
orientation and cell growth by strong static magnetic fields.
These new biomagnetic approaches will open new horizons in brain
research, brain treatment, and regenerative medicine.
details of the talk and a short biography of Professor Ueno are in the
attachment to this email
The seminar will be in PX001 in the Exhibition Centre of the University,
at 14:00 on the 2nd of September.
All welcome
--
Gary Green
York Neuroimaging Centre
The Biocentre
York Science Park
Innovation Way
Heslington
York
YO10 5DG
http://www.ynic.york.ac.ukhttps://www.ynic.york.ac.uk/about-us/people/ggrg
tel. +44 (0) 1904 435349
PA (Richard Lee) +44 (0) 1904 435329
fax +44 (0) 1904 435356
mobile +44 (0) 788 191 3004
We recently carried out an MRI study and (to keep it simple) we
compared two conditions A and B.
We found two regions that preferred A to B, region 1 and 2,
respectively.
I was keen to explore the time series a little further. So what I did
was take the A-B difference for each subject in each of the regions
and compute the 95%CI for each 2 sec interval from the start of the
stimulus presentation.
We get a difference time series for each region and for each point
we have a 95%CI. I have plotted the CIs for each point on each
function (one for region 1 and one for region 2).
Now I note at which time point the CIs reflect a sig diff (i.e., dont
cross the x axis) and what I find is that the critical difference
occurs earlier for region 1 than 2. At last a window on the time
course of psychological functioning?
I, of course, now want to claim my Nobel Prize but suspect this is
completely flawed.
Please advise.
Philip.
********************************************************************
Philip Quinlan E-Mail: ptq1(a)york.ac.uk
Department of Psychology FAX: (01904) 433181
The University of York Tel: (01904) 430000 Ext. 3135
Heslington Direct : (01904) 433135
York
YO10 5DD
U.K.
********************************************************************
I would be very grateful if the person who borrowed the book on
Magnetic Resonance Spectroscopy
edited by Matthews
could return it,
thanks
Gary
--
Gary Green
York Neuroimaging Centre
The Biocentre
York Science Park
Innovation Way
Heslington
York
YO10 5DG
http://www.ynic.york.ac.ukhttps://www.ynic.york.ac.uk/about-us/people/ggrg
tel. +44 (0) 1904 435349
PA (Richard Lee) +44 (0) 1904 435329
fax +44 (0) 1904 435356
mobile +44 (0) 788 191 3004
http://www.hindawi.com/journals/ijmms/2010/769780.html
********************************************************************
Philip Quinlan E-Mail: ptq1(a)york.ac.uk
Department of Psychology FAX: (01904) 433181
The University of York Tel: (01904) 430000 Ext. 3135
Heslington Direct : (01904) 433135
York
YO10 5DD
U.K.
********************************************************************
There is an additional seminar today
At 2pm
There will be a talk entitled
"NMR and MRI sensitivity enhancement by Parahydrogen Induced Polarization"
by
Kerstin Münnemann
Max Planck Institute for Polymer Research, Mainz, Germany
Despite its wide applicability in chemistry, biology and medicine,
Nuclear Magnetic Resonance (NMR) spectroscopy still suffers from its
inherently low sensitivity. Exploiting the large signal enhancements
associated with hyperpolarization techniques, such as Parahydrogen
Induced Polarization (PHIP), however, NMR or MRI qualify for monitoring
dynamic processes in real time. In this lecture, the synthesis and
hyperpolarization of several biocompatible molecules like barbiturates,
Vinylpyrrolinidon (blood plasma expander) or Dimethylcarboxylat
(precursor to fumarate) will be presented. Polarization transfer to 13C
in these molecules by using adequate pulse sequences is demonstrated.
Moreover, constant NMR signal enhancement of 1H and 13C is shown using a
continuous delivery of parahydrogen by hollow fiber membranes. This
allows the acquisition of two-dimensional NMR experiments requiring
multiple excitations with constant initial polarization. The membrane
technique can be easily extended to produce a continuous flow of a
hyperpolarized liquid as will be shown for MRI applications.
All welcome
Dear Users
Dear Users
Today (4-5 pm YNiC open plan) Matt Brookes from the University of
Nottingham will give a talk on "Brain network measurements using MEG
and ultra-high field MRI".
http://www.nottingham.ac.uk/neuroscience/contact/a-z/A-F/brookes_matt.phtml
Everyone is welcome to attend.
Best wishes
Rebecca
--
Dr. Rebecca E. Millman
York Neuroimaging Centre
The Biocentre
York Science Park
York
YO10 5DG
Email: rem(a)ynic.york.ac.uk
Tel: 01904 435 5373